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Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No. Product Name Inquiry
1446486-33-4
Tenofovir Disoproxil USP Related Compound B
Tenofovir Disoproxil USP Related Compound B is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS.
1449660-81-4
HIV-1 inhibitor-10
HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.
1451042-19-5
T326
145819-92-7
Emtricitabine triphosphate
(-)-Emtricitabine triphosphate, an antiviral drug, is commonly prescribed for HIV-1 infection. It suppresses virus replication by inhibiting the reverse transcriptase enzyme. Consequently, the viral load decreases, and immune efficacy increases, delaying the onset of AIDS.
1464851-21-5
(Z)-9-Propenyladenine
(Z)-9-Propenyladenine is a mutagenic impurity of tenofovir disoproxil fumarate. Tenofovir is a nucleotide analogue reverse transcriptase (NtART) inhibitor used as an antiretroviral drug.
147127-19-3
(S)-Tenofovir
One isomer impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor.
147127-20-6
Tenofovir
Tenofovir blocks reverse transcriptase and hepatitis B virus infections.
1473404-51-1
Hck-IN-1
Hck-IN-1 is a selective inhibitor of Nef-dependent Hck with IC50s of 2.8 and >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide antagonist of HIV-1 Nef with an IC50 of 100-300 nM for wild-type HIV-1 replication. It binds pocket residue Asn126 and has anti-retroviral activity.
147362-57-0
Loviride
Loviride is an RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection.
147468-65-3
HIV p17 Gag 77-85
HIV p17 Gag 77-85 is used in the research of anti-HIV.
147-84-2
Ditiocarb
148-18-5
Ditiocarb sodium
Ditiocarb sodium is a copper cementation rate accelerator that reduces the incidence of HIV infection. It also inhibits superoxide dismutase and has antioxidant and oxidant effects on cells.
149267-24-3
CGP 53820
CGP 53820 has been found to be a HIV-1 Protease pseudosymmetric inhibitor that could probably be effective in the treatment of HIV infections.
149488-17-5
Trovirdine
Trovirdine, a thiourea non-nucleoside reverse transcriptase inhibitor, was shown to inhibits HIV-1 RT when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate but inhibits has no development reported recently.
IC50: HI
149950-60-7
Emivirine
Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity.
149950-61-8
GCA-186
GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1,180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively.
150113-99-8
Decanoyl-RVKR-CMK
Decanoyl-RVKR-CMK is a proprotein convertase inhibitor and has been found to restrain regulated secretion of the neuronal polypeptide VGF in PC12 cells.
150378-17-9
Indinavir
Indinavir is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Indinavir is used as an antiviral.
150840-75-8
(3S,4S)-4-[8-[[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]amino]octanoylamino]-3-hydroxy-6-methylheptanoic acid
RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively.
152128-77-3
Emtricitabine S-Oxide
A metabolite of Emtricitabine.

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