Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
147127-20-6	Tenofovir Tenofovir blocks reverse transcriptase and hepatitis B virus infections.
1473404-51-1	Hck-IN-1 Hck-IN-1 is a selective inhibitor of Nef-dependent Hck with IC50s of 2.8 and >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide antagonist of HIV-1 Nef with an IC50 of 100-300 nM for wild-type HIV-1 replication. It binds pocket residue Asn126 and has anti-retroviral activity.
147362-57-0	Loviride Loviride is an RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection.
147468-65-3	HIV p17 Gag 77-85 HIV p17 Gag 77-85 is used in the research of anti-HIV.
147-84-2	Ditiocarb
148-18-5	Ditiocarb sodium Ditiocarb sodium is a copper cementation rate accelerator that reduces the incidence of HIV infection. It also inhibits superoxide dismutase and has antioxidant and oxidant effects on cells.
149267-24-3	CGP 53820 CGP 53820 has been found to be a HIV-1 Protease pseudosymmetric inhibitor that could probably be effective in the treatment of HIV infections.
149488-17-5	Trovirdine Trovirdine, a thiourea non-nucleoside reverse transcriptase inhibitor, was shown to inhibits HIV-1 RT when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate but inhibits has no development reported recently. IC50: HI
149950-60-7	Emivirine Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity.
149950-61-8	GCA-186 GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1,180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively.
150113-99-8	Decanoyl-RVKR-CMK Decanoyl-RVKR-CMK is a proprotein convertase inhibitor and has been found to restrain regulated secretion of the neuronal polypeptide VGF in PC12 cells.
150378-17-9	Indinavir Indinavir is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Indinavir is used as an antiviral.
150840-75-8	(3S,4S)-4-[8-[[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]amino]octanoylamino]-3-hydroxy-6-methylheptanoic acid RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively.
152128-77-3	Emtricitabine S-Oxide A metabolite of Emtricitabine.
153021-75-1	Trecovirsen
15324-64-8	Glycolithocholic acid 3-sulfate
154212-56-3	Cosalane
154598-52-4	(S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer.
1550053-02-5	BRD3308 BRD3308 is a highly selective HDAC3 inhibitor with IC50 of 54 nM. BRD3308 inhibits pancreatic β-cell apoptosis induced by inflammatory cytokines or glycolipid toxic stress, and increases the release of functional insulin. BRD3308 activates HIV-1 transcription and destroys the HIV-1 incubation period.
155148-31-5	AMD 3100 octahydrochloride AMD 3100 octahydrochloride is a high selective CXCR4 chemokine receptor antagonist (IC50 values are 0.02 - 0.13 and > 25 μM for CXCR4 and all other chemokine receptors respectively).

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