Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
129318-38-3	HIV gp120 (421-438)
129618-40-2	Nevirapine Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
129988-00-7	Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl
1300-94-3	Amylmetacresol Amylmetacresol (AMC) is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections. Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils.
130286-75-8	HIV-IN-8 HIV-IN-8 is a HIV inhibitor.
1312424-26-2	Rilpivirine-[d6] Rilpivirine-[d6] is the labelled analogue of Rilpivirine. Rilpivirine ia a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
1329613-10-6	Dapivirine-[d11] Dapivirine-[d11], is the labelled analogue of Dapivirine. Dapivirine is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibiting a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates.
1332879-52-3	Pitstop 2 Pitstop 2 is a selective clathrin-mediated endocytosis (CME) inhibitor that selectively inhibits the interaction between the clathrin terminal domain and amphiphysin with an IC50 of 12 μM. It inhibits HIV-1 entry and infection in HeLa reporting cell line, and also inhibits clathrin-independent endocytosis of CD44, CD98 and CD147 in HeLa cells. It can seriously interfere with synaptic vesicle circulation.
1333126-31-0	Azvudine hydrochloride Azvudine hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride inhibits NRTI-resistant viral strains.
133432-71-0	Peldesine Peldesine is a potent, competitive, reversible and orally active inhibitor of purine nucleoside phosphorylase (PNP) with IC50s of 36, 5 and 32 nM for human, rat and mouse red blood cell (RBC) PNP, respectively. It is also a T-cell proliferation inhibitor (IC50 = 800 nM), and has the potential for the study of cutaneous T-cell lymphoma, psoriasis and HIV infection.
1335210-23-5	1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic Acid 1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic Acid (CAS# 1335210-23-5) is used as an intermediate in the synthesis of GSK1265744 (I), a potent HIV integrase inhibitor.
134379-77-4	2',3'-Dideoxy-2',3'-didehydro-5-fluoro-cytidine It is a nucleoside reverse transcriptase inhibitor (NRTI) with the potential to inhibit HIV-1 replication.
134624-73-0	Stavudine sodium Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it. Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes.
1352879-65-2	PF-3450074 PF-3450074 is a HIV-1 inhibitor that targets HIV capsid protein.
135295-27-1	(2RS)-FPMPA
135525-71-2	L 696229
135525-77-8	L-697639
1356355-11-7	Saquinavir-[d9] A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases.
1357647-78-9	BRD-K98645985 BRD-K98645985 is a BAF inhibitor that binds ARID1A-specific BAF complexes, prevents nucleosomal positioning, and potently reverses HIV-1 latency, without T cell activation or toxicity.
136470-78-5	Abacavir Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.

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