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Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No. Product Name Inquiry
1051419-24-9
Nevirapine-[d3]
Nevirapine-[d3] is the labelled analogue of Nevirapine. Nevirapine is an anti-HIV drug that reduces the amount of virus in the body.
1054312-81-0
FK-3000
106060-92-8
AZT triphosphate tetraammonium
106362-32-7
Peptide T
Peptide T is an HIV entry inhibitor that acts by blocking chemokine-5 receptors (CCR5), currently under clinical trials for the treatment of HIV-related neurological and constitutional symptoms.
106362-34-9
Adaptavir
A CCR5 receptor antagonist. CCR5 antagonists block HIV from getting into and infecting certain cells of the immune system.
1067224-41-2
Epicoccone B
Epicoccone B, a natural product firstly reported from C. globosum, has anti-HIV activity. It has the ability of scavenging DPPH free radical with an IC50 of 10.8 μM, and has strong inhibitory effect on α-glucosidase with an IC50 of 27.3 μM.
1069-66-5
Sodium valproate
Valproic acid is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
1073897-80-9
1,3,5-tricaffeoylquinic acid
1,3,5-Tricaffeoylquinic acid is a tricaffeoylquinic acid derivative isolated from H. populifolium with anti-HIV effect.
1077-28-7
DL-Thioctic acid
Lipoic acid is a very excellent natural antioxidant, with free radical scavenging effect, its ability to remove free radicals is more than 100 times that of vitamin C, especially suitable for anti-aging products. It has the effect of chelating metal ions, can bind to copper ions in tyrosinase, is a competitive inhibitor of tyrosinase, and has good whitening effect. However, lipoic acid has the problems of low solubility, poor stability and significant odor, which limits its application in cosmetics. The shortcomings of lipoic acid can be solved by supramolecular inclusion technology. It can be widely used in anti-aging, wrinkle removal, whitening, spot lightening, anti-inflammatory and anti-sensitivity, acne treatment, scar reduction, damage repair and other products, and it is compatible with lotion cream formula, gel formula and water formula.
1092540-50-5
Atazanavir-[d6]
Atazanavir-[d6] is the labelled analogue of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-51-6
Atazanavir-[d9]
Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-52-7
Atazanavir-d18
Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-56-1
Atazanavir-d15
1092776-63-0
IT1t dihydrochloride
IT1t dihydrochloride is a potent and orally CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays).
1097628-00-6
Ainuovirine
1100750-98-8
Raltegravir-d6
1114507-62-8
HIV-1 inhibitor-61
111869-49-9
7-Deaza-2',3'-dideoxyguanosine
7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2',3'-dideoxynucleoside 5'-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM.
1132642-95-5
Efavirenz-[d5]
Efavirenz-[d5] is the labelled analogue of Efavirenz. Efavirenz is an antiretroviral medication used to treat and prevent HIV/AIDS.
1132747-14-8
Atazanavir-[d5]
Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.

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