Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
1077-28-7	DL-Thioctic acid Lipoic acid is a very excellent natural antioxidant, with free radical scavenging effect, its ability to remove free radicals is more than 100 times that of vitamin C, especially suitable for anti-aging products. It has the effect of chelating metal ions, can bind to copper ions in tyrosinase, is a competitive inhibitor of tyrosinase, and has good whitening effect. However, lipoic acid has the problems of low solubility, poor stability and significant odor, which limits its application in cosmetics. The shortcomings of lipoic acid can be solved by supramolecular inclusion technology. It can be widely used in anti-aging, wrinkle removal, whitening, spot lightening, anti-inflammatory and anti-sensitivity, acne treatment, scar reduction, damage repair and other products, and it is compatible with lotion cream formula, gel formula and water formula.
1092540-50-5	Atazanavir-[d6] Atazanavir-[d6] is the labelled analogue of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-51-6	Atazanavir-[d9] Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-52-7	Atazanavir-d18 Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1092540-56-1	Atazanavir-d15
1092776-63-0	IT1t dihydrochloride IT1t dihydrochloride is a potent and orally CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays).
1097628-00-6	Ainuovirine
1100750-98-8	Raltegravir-d6
1114507-62-8	HIV-1 inhibitor-61
111869-49-9	7-Deaza-2',3'-dideoxyguanosine 7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2',3'-dideoxynucleoside 5'-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM.
1132642-95-5	Efavirenz-[d5] Efavirenz-[d5] is the labelled analogue of Efavirenz. Efavirenz is an antiretroviral medication used to treat and prevent HIV/AIDS.
1132747-14-8	Atazanavir-[d5] Labelled Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir.
1133378-37-6	Darunavir-[d9] Darunavir-[d9] is a labelled Darunavir. Darunavir is an antiretroviral medication for the prevention of HIV/AIDS.
1133702-41-6	Fosamprenavir-d4 Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Anti-HIV infection.
113852-41-8	PMEDAP PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication with anti-murine cytomegalovirus (MCMV) activity, and is a very potent inhibitor of moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality. It has been studied for potential treatment of feline herpesvirus 1 (FHV-1).
1141453-73-7	Kuguacin N
1142096-06-7	Etravirine-[d6] Etravirine-[d6] is the labelled analogue of Etravirine. Etravirine is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor.
1149348-10-6	FGI-106-tetrahydrochloride FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI- 106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively.
114987-18-7	Adenallene
115416-08-5	HIV gp120 (308-331)

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