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Antiviral Drug Formulation Services

Antiviral drugs are available in a variety of dosage forms, such as oral liquid and solid dosage forms, parenteral formulations, ophthalmic, topical products for oral delivery, nasal/extra-nasal delivery, and pulmonary delivery. The selection of stable formulations ensures consistency in stability, hygroscopicity buccal delivery, nasal/intranasal delivery and pulmonary delivery. Scientists have been working on new formulations of antiviral drugs to improve the penetration.

BOC Sciences focuses on developing formulations that best fit the antiviral drug program. Our team is able to quickly and cost-effectively identify a stable, pharmacologically efficient dosage form for each formulation development project to ensure that it is optimal for the therapeutic indication and the intended route of administration.

Comprehensive Services

We ensure that pharmaceutical formulations of each antiviral drug are prepared and analyzed appropriately by following a standard formulation procedure. Our comprehensive antiviral drug formulation services include:

During the formulation development phase, we can evaluate the quality of different drug products in terms of stability, efficacy and processability. BOC Sciences supports different routes of administration, delivery systems and drug manufacturing technologies, including:

  • Suspensions (micro-suspensions and nano-suspensions)
  • Bottled active pharmaceutical ingredients
  • Micro-filling of active pharmaceutical ingredients
  • Dry mixing and pottingLiquid capsule filling
  • Spray drying
  • Dry/wet granulating and capsule filling/tableting
  • Direct tableting
  • Pouch filling

BOC Sciences has decades of experience in the development of antiviral drug formulations, and our dedicated team has extended its expertise to include high potency active pharmaceutical ingredients (HPAPI).

  • Comprehensive high potency antiviral drug formulation capabilities
  • Determine the optimal safe handling of formulations based on occupational exposure limits
  • Antiviral drug formulation risk assessment
  • Formulation Types
  • Oral: Solutions, suspensions, emulsions, capsules
  • Diets
  • Parenteral
  • Inhalation
  • Radiolabeled
  • Topical

Figure 1. Description of various hydrogel formulations of antiviral drugs. (Jacob, C.; et al. 2015)Figure 1. Description of various hydrogel formulations of antiviral drugs. (Jacob, C.; et al. 2015)

Formulation Facilities and Equipment

  • BOC Sciences is equipped with laboratories suitable for the preparation of antiviral dosing formulation. Each laboratory is capable of preparing any batch of formulations required for preclinical programs and eliminating cross-contamination. All of the formulated products are stored under pre-defined controlled conditions
  • Our analytical chemists are able to analyze dose formulations for identity, accuracy, homogeneity and stability

Expertise in Antiviral Drug Formulation

We can quickly develop the antiviral drug formulation that best fits your antiviral drug development program and can also provide submission-ready documentation.

  • Our knowledge of the physical properties of the antiviral APIs being used allows us to identify robust antiviral drug formulations
  • Based on the morphological characteristics, physicochemical properties and stability of the antiviral drug, we conduct the formulation process studies to initially determine the preparation process for laboratory samples and develop corresponding process control indicators
  • BOC Sciences has the equipment and instrumentation commonly used in antiviral drug formulation process and quality studies for a variety of preparations including tablets, injections, capsules, granules, ointments, creams, sprays, gels, syrups, tinctures, and oral liquid formulations
  • We have the capability to develop new technologies such as extended release formulations, nano formulations and fat emulsions

Why Partner with BOC Sciences?

  • We apply our years of proven expertise and experience in antiviral drug development to improve the success of your program
  • Our continuously updated facilities support a range of antiviral drug analysis and manufacturing services
  • BOC Sciences' experienced team of scientists and regulatory staffs are focused on working with our clients to deliver timely and high-quality small molecule antiviral drugs
  • Our partnerships with leading experts in emerging technologies allow us to apply innovative solutions to your antiviral drug research programs

Reference

  • Jacob, C.; et al. Hydrated polymer system as efficient carrier for the delivery of drugs against viral infections. International Journal of Drug Delivery Technology. 2015. 5(2): 43-47.

※ Please kindly note that our services are for research use only.

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