Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No.	Product Name	Inquiry
1401924-49-9	NVP018
140207-93-8	Pentosan Polysulfate Sodium Pentosan polysulfate sodium is a biomedical product used for treating interstitial cystitis, a chronic bladder condition causing pain and frequent urination. This compound acts as an anticoagulant and a urinary protectant, reducing inflammation and restoring the integrity of the bladder lining.
141117-12-6	Celgosivir hydrochloride Celgosivir hydrochloride is the hydrochloride salt of Celgosivir which is anα-glucosidase inhibitor and inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in vitro assay.
141237-50-5	HIV-1 Rev 34-50 HIV-1 Rev (34-50) is a 17-aa cell-penetrating peptide derived from HIV-1 Rev protein residue 34-50. It is an RNA-binding peptide that has been used to deliver macromolecules into cells.
141497-12-3	H-Gly-Pro-Gly-NH2 H-Gly-Pro-Gly-NH2 inhibits HIV-1 replication through its metabolite α-hydroxyglycineamide. It increases the antiviral activity of zidovudine and ritonavir.
1415559-43-1	CDK9-IN-1 Among CDKs, CDK9 is a validated pathological target in HIV infection, inflammation and cardiac hypertrophy; however selective CDK9 inhibitors are still not available. We present a selective inhibitor family of CDK9 based on the 4-phenylamino-6- phenylpyrimidine nucleus. We show a convenient synthetic method to prepare a useful intermediate and its derivatisation resulting in novel compounds. The CDK9 inhibitory activity of the derivatives was measured in specific kinase assay and the CDK inhibitory profile of the best ones (IC50 > 100nM) was determined. The most selective compounds had high selectivity over CDK1, 2, 3, 5, 6, 7 and showed at least one order of magnitude higher inhibitory activity over CDK4 inhibition. The most selective molecules were examined in cytotoxicity assays and their ability to inhibit HIV-1 replication was determined in cellular assays.
1416258-16-6	(±)-BI-D Approximately 2.4-2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160-200 nM, in Psip1 and double-KO cells.
141752-91-2	Pegaldesleukin
141790-23-0	Fozivudine tidoxil Fozivudine tidoxil, an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity, is a reverse transcriptase inhibitor potentially for the treatment of HIV infection. Fozivudine tidoxil, a member of the NRTI family, is incorporated into the newly synthesized DNA strand during intracellular viral replication and irreversibly binds to the viral RT, thereby disrupting the reverse transcription of the virus.
1423821-88-8	Tat-beclin 1 Tat-beclin 1 is a region of the autophagy protein, beclin 1, binding to HIV-1 Nef and inducing autophagy.
14261-92-8	APOBEC3G-IN-1
142629-81-0	Azt-pmap Azt-pmap, an aryl phosphate derivative of AZT, is a nucleoside analogue with anti-HIV activity.
1428535-92-5	ST7612AA1 ST7612AA1 is a potent Histone deacetylase (HDCA) inhibitor. It showed an in vitro activity in the nanomolar range associated with a remarkable in vivo antitumor activity.
1428729-63-8	RIG-1 modulator 1 RIG-1 modulator 1 is an inhibitor of HBV, HCV and HIV.
1428-95-1	5-(N,N-Hexamethylene)-amiloride 5-(N,N-Hexamethylene)-amiloride derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. It is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively.
1432060-78-0	Lopinavir-d7
144217-65-2	YYA-021 YYA-021 enhances the neutralization sensitivity of simian-human immunodeficiency virus (SHIV) carrying the envelope from the clade B clinical human immunodeficiency virus type 1 (HIV-1) isolate MNA.
1443460-91-0	GSK2838232 GSK2838232, a derivative of Betulin, is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection.
1443461-21-9	HIV-1 inhibitor-60 GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection. GSK2838232 is a betulin derivative. .
144606-93-9	(+)-Carbovir triphosphate

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