Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
1155419-89-8	BI 224436 BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of >90 μM.
1159840-61-5	Gardiquimod-diTFA Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM.
116249-65-1	Benanomicin A Benanomicin A is produced by the strain of Actinomadura sp. MH193-16F4. A and B have anti-candida, Cryptococcus neoforme, Saccharomyces cerevisiae and other fungal activities, while A has stronger activity. Xylose benamycin A and B showed similar or slightly stronger activity against candida, yeast and Cryptococcus, but decreased activity against aspergillus. The antifungal activity of 2-demethylbenamycin was similar to that of xylose Benamycin A. The synthesized 7-methoxybenamycin had little antifungal activity, but showed inhibitory activity of glucosinolase (EC 3.2.1.20) with IC50 of 60μg/mL.
1174719-68-6	WRNA10 WRNA10 is a potent HIV-1 TAR RNA binder with an IC50 of 10 µM and an CC50 of 40 µM.
117704-65-1	Pradimicin A Pradimicin A is an antibiotic produced by Actinomadura hibisca. It has strong antifungal and yeast activity.
1185237-51-7	Panobinostat-[d4] Panobinostat-[d4], is the labelled analogue of Panobinostat. Panobinostat is a drug for the treatment of various cancers. It is a hydroxamic acid and acts as a non-selective histone deacetylase inhibitor.
1185451-72-2	CXCR4 antagonist 7
1185878-98-1	Pentoxifylline-[d6] Pentoxifylline-[d6] is the labelled analogue of Pentoxifylline which is a competitive nonselective phosphodiesterase inhibitor.
1185995-18-9	Pentoxifylline-[d5] Pentoxifylline-[d5] is the labelled analogue of Pentoxifylline. Pentoxifylline can be used for the treatment of muscle pain in people with peripheral artery disease.
1187917-12-9	AIC-292 AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. It inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model.
1189471-66-6	rac α-Lipoic Acid-[d5] rac α-Lipoic Acid-[d5] is the labelled analogue of rac α-Lipoic Acid, which is a fat-metabolism stimulator.
1189657-87-1	Probenecid-d14 Probenecid-[d14] is the labelled analogue of Probenecid. Probenecid is a drug that increases the excretion of uric acid in the urine and can be used to treat gout and hyperuricemia.
1189994-89-5	5-Hydroxy Valproic acid-[d7] sodium salt 5-Hydroxy Valproic acid-[d7] sodium salt is the labelled analogue of 5-Hydroxy Valproic acid sodium salt, which is a metabolite of Valproic Acid.
119139-55-8	Interiorin Interiorin is a lignan isolated from Kadsura heteroclita. Interiorin exhibits anti-HIV activity.
1192224-24-0	Dealkyl Atazanavir An impurity of Atazanavir
1206161-97-8	Filgotinib Filgotinib is a potent and selective JAK1 inhibitor exhibiting 30-fold selectivity over JAK2. It was shown to inhibit Th1 and Th2 differentiation and to a lesser extent the differentiation of Th17 cells in vitro. Filgotinib has the potential for the treatment of rheumatoid arthritis and possibly other immune-inflammatory diseases.
121104-96-9	6-O-butyl castanospermine Celgosivir, an effective α-glucosidase I inhibitor, has been found to be related to viral maturation and is still under Phase I/II trial against Dengue. IC50: 16 and 47 umol/L (through plaque assay and a cytopathic assay).
1217629-70-3	Nelfinavir-[d3] Nelfinavir-[d3] is the labelled analogue of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor.
1217661-20-5	Amprenavir-[d4] Amprenavir-[d4] is a labelled analogue of Amprenavir. Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP.
1217819-15-2	Tipranavir-[d4] Tipranavir-[d4] is the labelled analogue of Tipranavir, which is a nonpeptidic HIV protease inhibitor and has been found to be effective as an antiviral.

※ Please kindly note that our services are for research use only.