Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No.	Product Name	Inquiry
1800570-92-6	CCR5 antagonist 3
1800570-93-7	CCR5 antagonist 2
1802998-75-9	Filgotinib maleate
1803444-21-4	GSK3739936 GSK3739936 (BMS-986180) is a potent HIV-1 allosteric integrase inhibitor with an IC50 value of 11.1 nM and an EC50 value of 1.7 nM. GSK3739936 is also a weak CYP inhibitor (IC50>24.3 μM). GSK3739936 shows favorable pharmacokinetic property in preclinical species with rapid absorption, low to moderate clearance and excellent oral bioavailability.
1810869-23-8	MK-8527
181701-06-4	Interiotherin A Interiotherin A is a lignan isolated from Schisandra sphenanthera. It shows anti-HIV activity.
181785-84-2	Elvucitabine
1818867-24-1	Fipravirimat Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research.
1818868-23-3	HIV-1 inhibitor-52
1821309-39-0	HIV-1-inhibitor-6 HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to drugs targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM.
182316-44-5	Cyclotriazadisulfonamide Cyclotriazadisulfonamide is a CD4-targeted HIV entry inhibitor. CADA inhibits HIV at submicromolar levels by specifically down-modulating cell-surface and intracellular CD4.
183904-53-2	(+)-Dihydrocalanolide A
184539-13-7	Teicoplanin sodium
185220-03-5	PNU‐142721
1854111-80-0	PB(OH)3
1854126-41-2	Chloroquine-[d5] Chloroquine-[d5], is the labelled analogue of Chloroquine. Chloroquine is an antimalarial agent.
1854126-42-3	Chloroquine-[d5] Diphosphate Chloroquine-[d5] Diphosphate, is the labelled analogue of Chloroquine Diphosphate. Chloroquine phosphate is an antimalarial drug and weak intercalating agent. It inhibits TLR signalling in plasmacytoid dendritic cells (pDCs). It has been used in emergency of COVID-19.
185897-02-3	Indinavir-[d6] Indinavir-[d6] is the labelled analogue of Indinavir, which is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. It is used as an antiviral.
1859189-55-1	BNM-III-170 BNM-III-170 can inhibit HIV-1 virus entry into target cells.
185991-07-5	AMD3465 hexahydrobromide AMD 3465 is a potent and selective antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells. AMD 3465 (50 nM) totally blocks CXCL12-induced calcium mobilization, with an IC50 of 17 nM, but shows no effect on the intracellular calcium fluxes elicited by the CCR5 ligands RANTES, LD78β and MIP-1β in U87.CD4.CCR5 cells. MD3465 was even 10-fold more effective as a CXCR4 antagonist, while showing no interaction whatsoever with CCR5. AMD3465 has the potential to mobilize hematopoietic stem cells.

※ Please kindly note that our services are for research use only.