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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Human papillomavirus (HPV)
Overview
Cervical cancer has become the seventh most common cancer and the fourth most common among women. In addition to serious health problems, HPV-related infections and cancers are a serious economic burden. Although no effective HPV inhibitors have been developed, several compounds and targets have been analyzed. E1 and E2 are the only two viral proteins necessary for HPV genome replication. In addition to targeting HPV proteins, the viral genome itself could be the target as well. Several sequence-specific DNA binding compounds belonging to the pyrrole-imidazole polyamide class have been developed. Currently, anti-HPV drugs are mainly oral hormonal drugs such as acyclovir, ganciclovir, interferon and interleukins.
Human papillomavirus (HPV), the most common sexually transmitted infection, is a virus with double-stranded circular DNA from the papillomavirus family. HPVs can cause numerous different cancers as well as benign lesions in the epithelia. The current situation in HPV therapy suggests that there is a need for specific drugs targeting HPV infection.
CAS No. | Product Name | Inquiry |
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1075281-70-7 |
Teslexivir-hydrochlorideTeslexivir (BTA074) hydrochloride is a potent antiviral agent. Teslexivir hydrochloride is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an association that is a necessary step in the DNA replication and thus viral production for Human Papilloma Virus (HPV) 6 and 11. Teslexivir hydrochloride can be used for condyloma research. |
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1075798-37-6 |
TeslexivirTeslexivir (BTA074) is a potent antiviral agent. Teslexivir is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an association that is a necessary step in the DNA replication and thus viral production for Human Papilloma Virus (HPV) 6 and 11. Teslexivir can be used for condyloma research. |
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1132749-48-4 |
Vorinostat-[d5]SAHA-d5 is a labelled suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor. |
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1429192-00-6 |
Retro-2Retro-2 is a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface between the endosome and trans-Golgi network. It has been shown to be effective against a range of bacterial and virus pathogens, both in vitro and in animal models. |
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331851-78-6 |
HPV18-IN-1HPV18-IN-1 (Compound H1) is a potent inhibitor of HPV18. HPV18-IN-1 prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation. HPV18-IN-1 has the potential for the research of cancer diseases. |
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402-71-1 |
Tosyl phenylalanyl chloromethyl ketoneTosyl phenylalanyl chloromethyl ketone (TPCK) is an irreversible inhibitor of chymotrypsin-like proteases. It also inhibits some cysteine proteases such as caspase, papain, bromelain or ficin. |
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4608-49-5 |
Larixyl acetateLarixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. |
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482646-13-9 |
A2ti-2A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. |
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570390-00-0 |
A2ti-1A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. |
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1332881-26-1 |
SabizabulinSabizabulin is a tubulin polymerization inhibitor with anti-tumor activity. |
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149647-78-9 |
VorinostatVorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. |
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