Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No.	Product Name	Inquiry
134624-73-0	Stavudine sodium Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it. Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes.
1352879-65-2	PF-3450074 PF-3450074 is a HIV-1 inhibitor that targets HIV capsid protein.
135295-27-1	(2RS)-FPMPA
135525-71-2	L 696229
135525-77-8	L-697639
1356355-11-7	Saquinavir-[d9] A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases.
1357647-78-9	BRD-K98645985 BRD-K98645985 is a BAF inhibitor that binds ARID1A-specific BAF complexes, prevents nucleosomal positioning, and potently reverses HIV-1 latency, without T cell activation or toxicity.
136470-78-5	Abacavir Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
136777-48-5	2-Cyclopentene-1-methanol,4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-,hydrochloride (1:1), (1S,4R)- Abacavir hydrochloride is a competitive, orally active nucleoside reverse transcriptase inhibitor. It can inhibits the replication of HIV. Abacavir hydrochloride shows anticancer activity in prostate cancer cell lines. Abacavir hydrochloride can trespass the blood-brain-barrier and suppresses telomerase activity.
136816-75-6	Atevirdine
136817-59-9	Delavirdine Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1.
13728-56-8	HIV-1 Nef-IN-1 HIV-1 Nef-IN-1, an inhibitor of HIV-1 Nef protein, can effectively compete for Nef-SH3Hck interactions with a Kd of 6.7 μM.
1374035-59-2	DMJ-I-228
137448-39-6	HIV-1-inhibitor-47 HIV-1 inhibitor-47 is an inhibitor of HIV-1, and inhibits vif-dependent degradation of human APOBEC3G, with an IC50 value of 14.33 μM. HIV-1 inhibitor-47 also involves in derivatives of 1-(2-pyrimidinyl)piperazine synthesis, with potential antianxiety, antidepressant, and antipsychotic effect.
137487-62-8	Alvircept sudotox
1391052-30-4	Lamivudine-13C-15N2 Lamivudine 13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus.
1392312-45-6	BMS-955176 BMS-955176 is the second generation HIV-1 maturation inhibitor.
139339-45-0	TOPOTECAN(TPT) Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects.
139694-65-8	KNI-102
139934-80-8	L 694746

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