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Antiviral API
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HIV-1 Nef-IN-1
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/13728-56-8.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 13728-56-8 |
| Description | HIV-1 Nef-IN-1, an inhibitor of HIV-1 Nef protein, can effectively compete for Nef-SH3Hck interactions with a Kd of 6.7 μM. |
Product Information
| Synonyms | 4-(3-Phenanthryl)butanoic acid; 3-Phenanthrenebutanoic Acid; 3-Phenanthrenebutyric Acid; NSC 92828; 3-(1-Phenanthryl)butanoic acid; 1-Phenanthrenepropanoic acid, β-methyl- |
| IUPAC Name | 4-phenanthren-3-ylbutanoic acid |
| Molecular Weight | 264.32 |
| Molecular Formula | C18H16O2 |
| Canonical SMILES | C1=CC=C2C(=C1)C=CC3=C2C=C(C=C3)CCCC(=O)O |
| InChI | InChI=1S/C18H16O2/c19-18(20)7-3-4-13-8-9-15-11-10-14-5-1-2-6-16(14)17(15)12-13/h1-2,5-6,8-12H,3-4,7H2,(H,19,20) |
| InChIKey | NYIVWTWKIQOBKO-UHFFFAOYSA-N |
| Boiling Point | 487.2±14.0°C (Predicted) |
| Melting Point | 138-139°C |
| Flash Point | 383.7°C |
| Purity | ≥95% |
| Density | 1.211±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in Chloroform (Slightly), DMSO (Slightly) |
| Appearance | Pale Yellow to Light Yellow Solid |
| Storage | Store at -20°C |
| Index Of Refraction | 1.678 |
| In Vitro | HIV-1 Nef-IN-1 (Compound D11; 20 μM) inhibits cell viability of COS7 cells, and the cell inhibition rate is 63.2. |
| PSA | 37.30000 |
| Target | HIV-1 Nef:6.7 μM (Kd) |
| Vapor Pressure | 2.63E-10mmHg at 25°C |
