2',3'-Dideoxy-2',3'-didehydro-5-fluoro-cytidine

Category	Human immunodeficiency Virus (HIV)
CAS	134379-77-4
Description	It is a nucleoside reverse transcriptase inhibitor (NRTI) with the potential to inhibit HIV-1 replication.

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Synonyms	FddddC; Dexelvucitabine; 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine; Reverset; DFC; 4-Amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydro-2-furanyl]-2(1H)-pyrimidinone
IUPAC Name	4-amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one
Molecular Weight	227.19
Molecular Formula	C9H10FN3O3
Canonical SMILES	C1=CC(OC1CO)N2C=C(C(=NC2=O)N)F
InChI	InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m0/s1
InChIKey	HSBKFSPNDWWPSL-CAHLUQPWSA-N
Boiling Point	394.9±52.0 °C(Predicted)
Flash Point	192.6°C
Purity	≥95%
Density	1.66±0.1 g/cm3(Predicted)
Solubility	Soluble in DMSO
Appearance	White to off-white (Solid)
Application	Anti-HIV Agents
Shelf Life	>2 years if stored properly
Storage	Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Complexity	405
Exact Mass	227.07061935
Index Of Refraction	1.665
PSA	90.37000
Target	Reverse Transcriptase; HIV
Vapor Pressure	7.15E-08mmHg at 25°C
XLogP3-AA	-1.3