-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
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- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- West Nile virus
- Antiviral intermediates
Ditiocarb sodium
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 148-18-5 |
| Description | Ditiocarb sodium is a copper cementation rate accelerator that reduces the incidence of HIV infection. It also inhibits superoxide dismutase and has antioxidant and oxidant effects on cells. |
Product Information
| Synonyms | Sodium diethyldithiocarbamate; Imuthiol; Thiocarb; Cupral; Carbamodithioic acid, diethyl-, sodium salt; Diethyldithiocarbamate; NSC 38583; Carbamodithioic acid, N,N-diethyl-, sodium salt (1:1) |
| IUPAC Name | sodium;N,N-diethylcarbamodithioate |
| Molecular Weight | 171.26 |
| Molecular Formula | C5H10NNaS2 |
| Canonical SMILES | CCN(CC)C(=S)[S-].[Na+] |
| InChI | InChI=1S/C5H11NS2.Na/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1 |
| InChIKey | IOEJYZSZYUROLN-UHFFFAOYSA-M |
| Boiling Point | 176.4°C at 760mmHg |
| Melting Point | 95°C |
| Flash Point | 60.5°C |
| Purity | ≥98% |
| Density | 1.1 g/cm3 |
| Solubility | Soluble in Alcohol, Acetone, Water; Insoluble in Ether, Benzene |
| Appearance | White or Slightly Brown or Slightly Pink Crystals |
| Application | Adjuvants, Immunologic; antiviral agents; chelating agents |
| Storage | Store at 2-8°C, sealed storage, away from moisture |
| In Vitro | Ditiocarb sodium (Sodium diethyldithiocarbamate) reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation. Ditiocarb sodium is an agent with strong antioxidant capacity and chelating activities. |
| In Vivo | Ditiocarb sodium (Sodium diethyldithiocarbamate) improves the depressed immune responses of newborn and aged mice. Sodium diethyldithiocarbamate prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity. In that AIDS model, Ditiocarb sodium reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival. |
| PSA | 88.32000 |
| Target | HIV |
