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Emtricitabine triphosphate

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Category Human immunodeficiency Virus (HIV)
CAS 145819-92-7
Description (-)-Emtricitabine triphosphate, an antiviral drug, is commonly prescribed for HIV-1 infection. It suppresses virus replication by inhibiting the reverse transcriptase enzyme. Consequently, the viral load decreases, and immune efficacy increases, delaying the onset of AIDS.
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Synonyms EMTRICITABINE TRIPHOSPHATE;CHEMBL341421;145819-92-7;EMTRICITABINE 5'-TRIPHOSPHATE;[[(2r,5s)-5-(4-Azanyl-5-Fluoranyl-2-Oxidanylidene-Pyrimidin-1-Yl)-1,3-Oxathiolan-2-Yl]methoxy-Oxidanyl-Phosphoryl] Phosphono Hydrogen Phosphate;((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl tetrahydrogen triphosphate;[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate;1RY;L-FSddCTP;Emtricitabine Triphosphate Sodium Salt;Discontinued See E525075;(-)-FTCTP;(-)-FTC-TP;BDBM50138405;HY-131596;CS-0137524;Q27452391;(-)-2',3'-Deoxy-5-fluoro-3'-thiacytidine-5'-triphosphate;EMTRICITABINE METABOLITE (EMTRICITABINE 5'-TRIPHOSPHATE);((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltetrahydrogentriphosphate;[[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate;TRIPHOSPHORIC ACID, P-(((2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-1(2H)-PYRIMIDINYL)-1,3-OXATHIOLAN-2-YL)METHYL) ESTER;
IUPAC Name [[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular Weight 487.19
Molecular Formula C8H13FN3O12P3S
Canonical SMILES O=P(O)(OP(O)(OP(O)(O)=O)=O)OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1
InChI InChI=1S/C8H13FN3O12P3S/c9-4-1-12(8(13)11-7(4)10)5-3-28-6(22-5)2-21-26(17,18)24-27(19,20)23-25(14,15)16/h1,5-6H,2-3H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16)/t5-,6+/m0/s1
InChIKey WIEOLFZNMKSGEX-NTSWFWBYSA-N
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

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