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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Reverse Transcriptases (RTs)
CAS No. | Product Name | Inquiry |
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EFdA-TP-tetraammoniumEFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetraammonium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetraammonium inhibits HIV-1 RT with multiple mechanisms |
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EFdA-TP-tetrasodiumEFdA-TP tetrasodium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms. |
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FNC-TP-trisodiumFNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. |
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1051418-95-1 |
Nevirapine-[d4]Nevirapine-[d4] is the labelled analogue of Nevirapine, which is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. |
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1051419-24-9 |
Nevirapine-[d3]Nevirapine-[d3] is the labelled analogue of Nevirapine. Nevirapine is an anti-HIV drug that reduces the amount of virus in the body. |
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106941-25-7 |
AdefovirUsed as an antiviral. |
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1132642-95-5 |
Efavirenz-[d5]Efavirenz-[d5] is the labelled analogue of Efavirenz. Efavirenz is an antiretroviral medication used to treat and prevent HIV/AIDS. |
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1142096-06-7 |
Etravirine-[d6]Etravirine-[d6] is the labelled analogue of Etravirine. Etravirine is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor. |
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1219803-67-4 |
Stavudine-[d4]An isotope labelled Stavudine. Stavudine is an antiretroviral medication used to prevent and treat HIV/AIDS. |
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1236287-04-9 |
Tenofovir maleateTenofovir hydrate reduces the viral cytopathic effect of HIV-1(IIIB), HIV-2(ROD) and HIV(EHO) with EC50 of 1.15 μg/mL, 1.12 μg/mL and 1.05 μg/mL in MT-4 cells. Tenofovir hydrate also reduces the viral cytopathic effect of SIV(mac251) , SIV(B670) ,SHIV(89.6) and SHIV(RTSHIV). Tenofovir hydrate inhibits hepatitis B virus (HBV) activity in HepG2 2.2.15, HepAD38 and HepAD79 cells. Tenofovir hydrate (4 μM) completely inhibits the growth of HIVIIIB in MT-2 cells. Tenofovir hydrate inhibits synthesis of negative strand strong-stop DNA with IC50 of 9 ?M for wild-type RT, 6 ?M for M184V RT and 50 ?M for K65R RT.Tenofovir hydrate (30 mg/kg) completely prevents SIV infection in all macaques without toxicity. Tenofovir hydrate treatment reduces plasma viral RNA levels to undetectable, with parallel decreases in the infectivity of plasma and infectious cells in peripheral blood mononuclear cells and cerebrospinal fluid (CSF) and stabilization of CD4+ T-cell numbers. Tenofovir hydrate (30 mg/kg, s.c.) completely abrogates HIV infection via intravaginal exposure in pig-tailed macaques. |
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1246812-58-7 |
rac Efavirenz-[d4]Rac Efavirenz-[d4] is an isotope compound of rac Efavirenz. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer. |
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7585-39-9 |
β-Cyclodextrinβ-cyclodextrin is a cyclic oligosaccharide produced from starch via enzymatic conversion. It is widely used in food, medicine, cosmetics, chemical and other industries. β-cyclodextrin is used as a complexing agent in drug delivery, increasing the water solubility, dissolution rate and bioavailability of poorly water-soluble drugs. β-Cyclodextrin is commonly used to produce HPLC columns that allow the separation of chiral enantiomers. |
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1142095-93-9 |
Etravirine-[d4]Etravirine-[d4] is the labelled analogue of Etravirine, which is a drug used for the treatment of HIV and a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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244767-67-7 |
DapivirineDapivirine, also known as TMC 120, TMC 120 R147681, is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibiting a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. |
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147221-93-0 |
Delavirdine mesylateDelavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1. |
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202138-50-9 |
Tenofovir Disoproxil FumarateTenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate. |
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500287-72-9 |
RilpivirineA novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. |
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1392275-56-7 |
Tenofovir alafenamide hemifumarateTenofovir alafenamide hemifumarate, also known as Tenofovir alafenamide fumarate (2:1), is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevents HIV from multiplying and can reduce the amount of HIV in the body. |
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1011529-10-4 |
AzvudineAzvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV. |
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23094-69-1 |
corilaginCorilagin, a gallotannin, inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows good anti-tumor activity on hepatocellular carcinoma and ovarian cancer. Corilagin shows a low level of toxicity toward normal cells and tissues. |
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