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Lamivudine Triphosphate

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Category Hepatitis B Virus (HBV)
CAS 143188-53-8
Description 3TCTP is a dideoxynucleoside analog and an inhibitor of reverse transcriptase that exhibit antiviral effect in vivo.
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Product Information

Synonyms Lamivudine Triphosphate;3TC-TP;143188-53-8;3TCTP;Lamivudine 5'-triphosphate;3TC Triphosphate;CHEMBL1230;RM8Y5KG43V;Triphosphoric acid, P-(((2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl)methyl) ester;Epivir triphosphate;[[(2R,5S)-5-(4-amino-2-oxo-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate;1RZ;L-SddCTP;LamivudineTriphosphate;(-)-SddCTP;Lamivudine-5'-triphosphate;UNII-RM8Y5KG43V;SCHEMBL12595501;DTXSID101343929;(-)3TC-5'TP;BDBM50138406;[[(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;CAS 143188-53-8;Q27452393;(-)-.beta.-L-2'-Deoxy-3'-thiacytidine-5'-triphosphate;[(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate;[[(2R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate;[[[5-(4-amino-2-oxo-1H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid;
IUPAC Name [[(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular Weight 469.20
Molecular Formula C8H14N3O12P3S
Canonical SMILES O=P(O)(OP(O)(OP(O)(O)=O)=O)OC[C@@H]1O[C@H](N2C=CC(N)=NC2=O)CS1
InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1
InChIKey YLEQMGZZMCJKCN-NKWVEPMBSA-N
Boiling Point 794.4±70.0°C at 760 mmHg
Purity ≥95% by HPLC
Density 2.38±0.1 g/cm3
Solubility Soluble in Methanol (Slightly), Water (Slightly, Sonicated)
Appearance clear aqueous solution
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

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