-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Ulonivirine
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 1591823-76-5 |
| Description | Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. |
Product Information
| Synonyms | Ulonivirine|UNII-4NS011EGKZ|4NS011EGKZ|3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl)methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile|3-chloro-5-[6-oxo-1-[[6-oxo-5-(trifluoromethyl)-1H-pyridazin-3-yl]methyl]-4-(trifluoromethyl)pyrimidin-5-yl]oxy-benzonitrile|SCHEMBL15633077|WHO 12037|MK-8507|HY-147411|CS-0564146|1591823-76-5|Benzonitrile, 3-chloro-5-((1-((1,6-dihydro-6-oxo-5-(trifluoromethyl)-3-pyridazinyl)methyl)-1,6-dihydro-6-oxo-4-(trifluoromethyl)-5-pyrimidinyl)oxy)- |
| Molecular Weight | 491.73 |
| Molecular Formula | C18H8ClF6N5O3 |
| Canonical SMILES | C1=C(C=C(C=C1OC2=C(N=CN(C2=O)CC3=NNC(=O)C(=C3)C(F)(F)F)C(F)(F)F)Cl)C#N |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 1020 |
| Exact Mass | 491.0219858 |
| Target | Reverse Transcriptase; HIV |
| XLogP3-AA | 2.7 |