Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
36703-88-5	Isoprinosine Isoprinosine is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine with the ratio of 3:3:1. It is an immunomodulatory drug approved in several countries for the treatment of viral infections.
368874-34-4	TC14012 TC 14012 is an antagonist of CXCR4.
371137-60-9	Antiviral agent 55
372087-80-4	DQBS
37300-21-3	Xylan polysulfate Xylan polysulfate is a semi-synthetic polysulfated xylan as a sulfated pentose polysaccharide with heparin-like properties.
374067-85-3	HIV-1 inhibitor-48
374679-27-3	Vif-ElonginC interaction inhibitor 1
377724-68-0	Melliferone Melliferone is a triterpenoid isolated from Brazilian propolis. It has anti-HIV activity.
379270-38-9	GS-7340 fumarate Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function.
380378-81-4	BILR 355
388604-55-5	CK-548
38954-02-8	Icariside D2 Icariside D2 is isolated from the fruits of Annona glabra. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0±1.0 uM, and it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells.
39111-07-4	Nigranoic acid Nigranoic acid is a natural product, and inhibits HIV-1 reverse transcriptase. Nigranoic acid exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model.
395069-92-8	MPG, HIV related MPG, a 27-AA peptide derived from the nucleotide localization sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41, is an effective nucleic acid and oligonucleotide carrier for wide delivery into cultured cells.
397878-17-0	Deaminase inhibitor-1
4097-22-7	2',3'-Dideoxyadenosine It is a potent anti-HIV agent.
410544-95-5	L-870810
41135-06-2	Inophyllum B
41692-24-4	16,16-Dimethyl prostaglandin A1 16,16-Dimethyl prostaglandin A1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis.
416971-40-7	HIV-1-inhibitor-37 HIV-1 inhibitor-37 (Compound 83) is a potent HIV-1. HIV-1 inhibitor-37 has the potential for further development as novel latency reversing agents.

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