Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
431980-38-0	RN-18 RN-18, a selective inhibitor of virion infectivity factor (Vif) APOBEC interactions and HIV-1 replication (IC50= 6 μM in nonpermissive H9 cells), antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G.
4373-41-5	Maslinic acid Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, such as antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating.
442633-00-3	CK-666 CK 666 has been found to be an inhibitor of the Arp2/3 complex and could also restrain actin polymerization.
452296-83-2	BMS 488043 BMS-488043 is a small-molecule HIV fusion inhibitor.
459-86-9	Mitoguazone Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation.
459929-62-3	HIV-IN-5 HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket).
461023-63-2	Aplaviroc-hydrochloride Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
461443-59-4	Aplaviroc Aplaviroc is a potent non-competitive CCR5 receptor allosteric antagonist with IC50 of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
473-90-5	Mesoxalate
473921-12-9	Lersivirine Lersivirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for the treatment of HIV-1 infection. It prevents HIV from entering the nucleus of healthy CD4 cells, which prevents the cells from producing new virus and decreases the amount of virus in the body.
476-69-7	Corydine Corydine is an alkaloid found primarily in the Corydalis genus of plants, known for its potential analgesic, antineoplastic, antimicrobial, anti-inflammatory, and neuroprotective effects. It interacts with neurotransmitter systems in the brain, making it a subject of interest for research into pain relief and neurological health.
497836-10-9	D77 D77 is anti-HIV-1 inhibitor, which inhibits HIV-1(IIIB) replication (EC50=23.8 μM)
501081-38-5	FGI-106 FGI-106, a potent and broad-spectrum inhibitor, has inhibitory activity against a variety of viruses with EC50s of 100, 800 and 400-900 nM against Ebola, Rift Valley and Dengue Fever viruses, respectively. It also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 and 150 nM, respectively.
51-21-8	5-Fluorouracil Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS).
524055-95-6	Antiviral agent 56
52557-26-3	Ingenol-3-palmitate Ingenol 3-palmitate is extracted from the latex of Euphorbia serrata. It displays cocarcinogenic and irritant activity on mouse ear and mice back skin.
528893-52-9	PKF050-638 PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction.
54-05-7	Chloroquine An antimalarial agent.
544467-07-4	HIV-1 integrase inhibitor HIV-1 integrase inhibitor is uesful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome.
54706-70-6	13-Oxyingenol-13-dodecanoate 13-Oxyingenol Dodecanoate is a derivative of Ingenol acts as a diterpene compound with antinematodal activity.

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