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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Human immunodeficiency Virus (HIV)
CAS No. | Product Name | Inquiry |
---|---|---|
2055732-24-4 |
ClaficapavirClaficapavir, a specific nucleocapsid protein (NC) inhibitor with an IC50 of about 1 μM, strongly binds to HIV-1 NC (Kd = 20 nM) thereby inhibiting the chaperone properties of NC and resulting in good antiviral activity against HIV-1. |
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206184-49-8 |
Tenofovir hydrateTenofovir(GS 1278, PMPA) is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. |
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2097938-51-5 |
R-10015R-10015 is an LIM domain kinase (LIMK) inhibitor that acts as a broad-spectrum antiviral drug for HIV infection. R-10015 blocks LIMK activity by binding to the ATP-binding pocket. |
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2098497-25-5 |
Decanoyl-RVKR-CMK-TFADecanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication. |
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210584-54-6 |
Amustaline dihydrochlorideAmustaline dihydrochloride is a nucleic acid targeted alkylator that is an effective pathogen inactivation agent for blood components containing red blood cells. It has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products). |
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2132412-25-8 |
CI-39CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 µM and an CC50 of >30 µM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup. |
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2132412-77-0 |
HIV-1-inhibitor-30HIV-1 inhibitor-30 (compound 10i) is a potent HIV-1 inhibitor with an EC50 value of 40 nM and an IC50 value of 80 nM for HIV-1 RT DNA polymerase. HIV-1 inhibitor-30 has highly antiretroviral activity against seven non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains (RT-K103N; RT-Y181C; RT K103N,Y181C; RT-L100I,K103N; RT-Y188L; RT-K103N,G190A; RT-K103N,V108I) with IC50s of 0.04~1.42 μM. HIV-1 inhibitor-30 can be used for researching AIDS. |
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2138861-99-9 |
ABBV-744ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. |
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216699-07-9 |
Abacavir sulfateAbacavir is an antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC50 value of 5.3 μM. |
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2170506-18-8 |
HIV-1-inhibitor-36HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1. HIV-1 inhibitor-36 has the potential for further development as novel latency reversing agent. |
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217082-57-0 |
Apelin-17 (Human, Bovine)Apelin-17 (human, bovine) is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 2.5 nM that is secreted by adipocytes. It potently inhibits forskolin-stimulated cAMP production in vitro. |
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217178-62-6 |
StampidineStampidine is a possible next-generation Pre-exposure prophylaxis (PrEP) candidate to prevent the sexual transmission of HIV-1. |
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2189684-45-3 |
GS-CA-1GS-CA-1 is a novel HIV capsid inhibitor developed by Gilead, which is a promisingly long-acting antiretroviral (ARV) agent. The preclinical study showed that GS-CA-1 could inhibit HIV-1 replication in human peripheral blood mononuclear cells (PBMCs) (EC50 = 140 pM). |
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219944-39-5 |
Isoescin IASource from the herbs of Aesculus hippocastanum L. |
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220408-24-2 |
HIV-1-TAT(48-60)HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. |
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220751-00-8 |
Hypoglaunine DHypoglaunine D, an analogue of triptonine B, is an anti-HIV compound that inhibits HIV replication in H9 lymphocytes with an EC50 of 22 μg/mL. |
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2234273-72-2 |
NBD-14189NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV 1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50<200 nM). |
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223769-59-3 |
HIV-Protease-Substrate-1HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease. |
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2245231-10-9 |
PirmitegravirPirmitegravir is a potent and first-in-class allosteric integrase (ALLINI) inhibitor that targets LEDGF/p75 binding site, and has excellent antiviral and safety properties. It shows picomolar IC50 in human PBMCs with a therapeutic index of >24000 for HIV-1. |
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2248124-46-9 |
HIV-1-protease-IN-2HIV-1 protease-IN-2 is a potent HIV-1 protease inhibitor with an IC50 of 2.53 nM. HIV-1 protease-IN-2 shows antiviral activity against DRV (Darunavir)-sensitive or DRV-resistant HIV-1 variants. |
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