Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
497836-10-9	D77 D77 is anti-HIV-1 inhibitor, which inhibits HIV-1(IIIB) replication (EC50=23.8 μM)
501081-38-5	FGI-106 FGI-106, a potent and broad-spectrum inhibitor, has inhibitory activity against a variety of viruses with EC50s of 100, 800 and 400-900 nM against Ebola, Rift Valley and Dengue Fever viruses, respectively. It also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 and 150 nM, respectively.
51-21-8	5-Fluorouracil Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS).
528893-52-9	PKF050-638 PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction.
54-05-7	Chloroquine An antimalarial agent.
544467-07-4	HIV-1 integrase inhibitor HIV-1 integrase inhibitor is uesful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome.
558447-26-0	AMD-070 AMD-070 is a potent and selective antagonist of CXCR4 (with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay).
55954-61-5	Pseudohypericin Pseudohypericin, which can be found in the herbs of Hypericum perforatum L, is implicated in the antidepressant efficacy of St. John's wort.
582-24-1	2-Hydroxyacetophenone 2-Hydroxyacetophenone (CAS# 582-24-1) is a useful reactant for synthesis of diarylpyrazoles as cyclooxygenase 2 inhibitors.
583836-55-9	Cys-TAT (47-57) It is an arginine-rich cell-penetrating peptide derived from HIV-1 transactivator protein.
59-48-3	Diclofenac EP Impurity E Diclofenac EP Impurity E is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID).
5948-75-4	gp120-IN-1 gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 µM and CC50 of 100.90 µM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells.
595-33-5	Medroxyprogesterone Acetate EP Impurity G Medroxyprogesterone Acetate EP Impurity G is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2. Medroxyprogesterone Acetate EP Impurity G is a manufactured hormone of the progestin type.
599179-03-0	Vicriviroc maleate Vicriviroc maleate is a CCR5 antagonist.
61413-54-5	Rolipram Rolipram is a selective PDE4 inhibitor that modulates cyclic AMP (cAMP) degradation. Study showed that rolipram induced neuronal differentiation of human bone marrow-mesenchymal stem cells (hBM-MSCs). It can be used as an anti-inflammatory agent.
614-60-8	trans-2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is found in the herbs of Angraecum fragrans, it has photooxidant activity.
624-49-7	Dimethyl fumarate Dimethyl fumarate is a Nrf2 activator used to treat adults with relapsing forms of multiple sclerosis.
634907-30-5	Censavudine Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials.
63585-09-1	Foscarnet sodium Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV.
64009-84-3	IMB-301 IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G, a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication), blocks hA3G-Vif interaction and inhibits Vif-mediated hA3G degradation. It inhibits HIV-1 replication in H9 cells with an IC50 of 8.63 uM.

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