Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
70288-86-7	Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis.
7057-48-9	beta-L-D4A beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.
7081-36-5	Leptomycin-A Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B.
70831-56-0	L-Chicoric acid Cichoric acid, that can be isolated from the herbs of Echinacea purpurea, has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. Chicoric acid may reduce acute alcohol-induced steatosis in mice through interfering with the induction of iNOS and iNOS-dependent signaling cascades in the liver. Chicoric acid also inhibited cell viability and induced apoptosis in 3T3-L1 preadipocytes which was characterized by chromatin condensation and poly ADP-ribose-polymerase (PARP) cleavage.
71247-78-4	Salaspermic acid Salaspermic acid is a natural triterpenoid compound found in several plants.
716354-86-8	CCR5 antagonist 1 CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2 that can inhibit HIV replication.
71678-03-0	Ilimaquinone Ilimaquinone is a marine sponge metabolite with antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. Ilimaquinone significantly enhanced TRAIL-induced apoptosis in HCT 116 cells and sensitized colon cancer cells to TRAIL-induced apoptosis through increased caspase-8, -3 activation, PARP cleavage, and DNA damage. Ilimaquinone also reduced the cell survival proteins Bcl2 and Bcl-xL, while strongly up-regulating death receptor (DR) 4 and DR5 expression.
71965-57-6	Globotriaosylceramide (porcine RBC) Globotriaosylceramide is a synthetic compound utilized for studying Anderson-Fabry disease. Acting as a substrate for enzymes, it aids in the research of this lysosomal storage disorder.
72029-21-1	ddATP-trisodium ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection.
729607-74-3	BMS-707035 BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM.
73465-43-7	1-Deoxymannojirimycin HCl It is an inhibitor of α-D-mannosidases (jack bean and calf liver) and mammalian α-L-fucosidase, but it has no glucosidase inhibitory properties.
73536-69-3	Bifendate Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage.
748146-89-6	CDK9-IN-30
74817-61-1	Murabutide Murabutide is a safe synthetic immunomodulator derived from muramyl dipeptide (MDP), the smallest bioactive unit in bacterial peptidoglycan. Murabutide has the ability to work synergistically with selected therapeutic cytokines to drive Th1 cytokine release. Murabutide has been found to inhibit human immunodeficiency virus type 1 (HIV-1) replication in macrophages by regulating the expression of cytokines required for different steps in the viral replication cycle.
7481-89-2	Zalcitabine Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
75580-37-9	Luzopeptin A Luzopeptin A is a cyclic depsipeptide antibiotic produced by an actinomycete strain. It has anti-tumor activity. It is a potent inhibitor of HIV-1 reverse transcriptase.
763903-67-9	Fosalvudine tidoxil
77286-66-9	(R)-Edelfosine (R)-Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. It induces apoptosis in human promyelocytic HL-60 leukemic cells and promonocytic U937 leukemic cells.
78860-37-4	Hinnuliquinone
80930-74-1	Zingibroside R1 Zingibroside R1 is a triterpenoid showing anti-tumor, anti-angiogenic and anti-HIV-1 activity.

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