Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
2765293-30-7	HIV-1-protease-IN-1 HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against HIV strain Indie.
27740-01-8	Scutellarin Scutellarin has been shown to induce apoptosis of ovarian and breast tumor cells in vitro.
28302-36-5	Sodium copper chlorophyllin B Sodium copper chlorophyllin B has antiviral activities against Influenza virus and HIV with IC50s of 50-100 μM.
284661-68-3	DPC-681 DPC-681, sulfonamide derivatives, is an extremely potent and selective inhibitor of HIV protease. IC90s: wild-type HIV-1=4-40 nM
28656-91-9	(+)-Aeroplysinin-1 (+)-Aeroplysinin-1 is a metabolite originally isolated from the marine sponge V. aerophoba with diverse biological activity. It is a tertiary alcohol.
301297-45-0	IQP-0528 IQP-0528 is a non-nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection. IQP-0528 works by blocking virus entry and has shown antiviral activity as microbicide gels.
301357-74-4	HIV-IN-6 HIV-IN-6 is a HIV-(cid:0) viral replication inhibitor by targeting Src family kinases (SFK) that interact with Nef protein of the virus, such as Hck.
30462-35-2	Theaflavin 3,3'-digallate Theaflavin 3,3'-digallate is a flavonoid isolated from Black tea. It is a good antitumor agent as well.
3056-17-5	Stavudine Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.
306305-07-7	4'-Ethynyl-2'-deoxyadenosine 4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
313682-08-5	Brecanavir Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir.
32909-92-5	Sulfametrole Sulfametrole is an orally active and potent antibacterial. Sulfametrole can be used for infections research, such as HIV, severe pneumonia and UTIs (urinary tract infections).
32981-85-4	(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate is an intermediate in the preparation of potent anticancer drug Paclitaxel.
332947-35-0	HIV-1-inhibitor-46 HIV-1 inhibitor-46 (compound 13d) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor with an EC50 value of 1.425 μM. HIV-1 inhibitor-46 can be used for the research of AIDS.
333352-59-3	NBD-557 NBD-557 is a N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analog, a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120-CD4 interaction,
333353-44-9	NBD-556 NBD-556 is small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. The CD4-induced conformational change in gp120 is necessary for interaction with CCR5.
333994-00-6	TAK-220 TAK-220 is an orally bioavailable small-molecule CCR5 antagonist.
339-72-0	L-Cycloserine It is produced by the strain of Erwinia uredovora 821. L-cycloserine is an excitatory amino acid that is effective against Mycobacterium tuberculosis. It has anti-gram-negative bacterial activity.
345909-03-7	Valproic acid-[4,4,4',4'-d4] One of the isotopic labelled form of Valproic Acid, which could be used as an antiepileptic agent.
35375-29-2	Amphotericin B methyl ester hydrochloride Amphotericin B methyl ester hydrochloride, a methyl ester derivative of the polyene antibiotic Amphotericin B, is a cholesterol binding compound with significant antifungal activity. It disrupts the production of HIV-1 particles and effectively inhibits HIV-1 replication.

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