Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No.	Product Name	Inquiry
5496-35-5	I-XW-053 I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-NTD interface) with micromolar affinity.
55497-79-5	Myriceric acid B Myriceric acid B isolated from the root bark of Myrica cerifera L. It exhibits cytotoxic activity towards the MOLT-3 cell line.
558447-26-0	AMD-070 AMD-070 is a potent and selective antagonist of CXCR4 (with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay).
55954-61-5	Pseudohypericin Pseudohypericin, which can be found in the herbs of Hypericum perforatum L, is implicated in the antidepressant efficacy of St. John's wort.
561022-65-9	Alloc-DOX
56317-05-6	Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside
582-24-1	2-Hydroxyacetophenone 2-Hydroxyacetophenone (CAS# 582-24-1) is a useful reactant for synthesis of diarylpyrazoles as cyclooxygenase 2 inhibitors.
583836-55-9	Cys-TAT (47-57) It is an arginine-rich cell-penetrating peptide derived from HIV-1 transactivator protein.
59-48-3	Diclofenac EP Impurity E Diclofenac EP Impurity E is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID).
5948-75-4	gp120-IN-1 gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 µM and CC50 of 100.90 µM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells.
595-33-5	Medroxyprogesterone Acetate EP Impurity G Medroxyprogesterone Acetate EP Impurity G is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2. Medroxyprogesterone Acetate EP Impurity G is a manufactured hormone of the progestin type.
599179-03-0	Vicriviroc maleate Vicriviroc maleate is a CCR5 antagonist.
61413-54-5	Rolipram Rolipram is a selective PDE4 inhibitor that modulates cyclic AMP (cAMP) degradation. Study showed that rolipram induced neuronal differentiation of human bone marrow-mesenchymal stem cells (hBM-MSCs). It can be used as an anti-inflammatory agent.
614-60-8	trans-2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is found in the herbs of Angraecum fragrans, it has photooxidant activity.
6152-57-4	3-O-Methylviridicatin O-Methylviridicatin is a metabolite produced by several species of Penicillium. It blocks TNF-alpha activation of the HIV LTR in the Hela-based system, with an IC50 of 5 mM, and inhibits virus production in the OM-10.1 cell line, a model of chronic infection responsive to induction by TNF-alpha, with an IC50 of 2.5 mM.
619331-12-3	BMS-585248 BMS585248 is a highly potent and novel human immunodeficiency virus type 1 (HIV-1) attachment inhibitor with 4-fluoro-6-azaindole core heterocycles. It targets the viral envelope protein gp120. It showed much improved in vitro potency and pharmacokinetic properties than the previous clinical candidate BMS488043.
624-49-7	Dimethyl fumarate Dimethyl fumarate is a Nrf2 activator used to treat adults with relapsing forms of multiple sclerosis.
634600-55-8	(Rac)-Saphenamycin It is a phenazine antibiotic produced by the strain of Str. canarius MG 314-hF8. It has strong effect against gram-positive bacteria and mycobacterium. It inhibits mouse leukemia L5178Y and L1210 cells with ID50 (μg/mL) of 0.15 and 0.6-2.5, respectively (in vitro determination).
634907-30-5	Censavudine Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials.
63585-09-1	Foscarnet sodium Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV.

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