Icariside D2

Category	Human immunodeficiency Virus (HIV)
CAS	38954-02-8
Description	Icariside D2 is isolated from the fruits of Annona glabra. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0±1.0 uM, and it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells.

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Synonyms	Icariside D2;38954-02-8;(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;IcarisideD2;CHEBI:182721;DTXSID001318054;HY-N7450;AKOS040761858;4-beta-D-Glucopyranosyloxybenzeneethanol;NCGC00385783-01;DA-54230;CS-0129180;G14608;4-(2-Hydroxyethyl)phenyl-beta-D-glucopyranoside;NCGC00385783-01_C14H20O7_4-(2-Hydroxyethyl)phenyl beta-D-glucopyranoside;
IUPAC Name	(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular Weight	402.4
Molecular Formula	C21H26N2O6
Canonical SMILES	CC(C)[C@@H]1CC2=CC(=C(N=C2C3=CC(=O)C(=CN13)C(=O)O)OC)OCCCOC
InChI	InChI=1S/C14H20O7/c15-6-5-8-1-3-9(4-2-8)20-14-13(19)12(18)11(17)10(7-16)21-14/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1
InChIKey	OJDSCNUKKOKOQJ-RKQHYHRCSA-N
Purity	98.0%
Appearance	Solid
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)