Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
21085-60-9	Calcium mesoxalate
2109805-83-4	UMB-136
2132412-25-8	CI-39 CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 µM and an CC50 of >30 µM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup.
2132412-77-0	HIV-1-inhibitor-30 HIV-1 inhibitor-30 (compound 10i) is a potent HIV-1 inhibitor with an EC50 value of 40 nM and an IC50 value of 80 nM for HIV-1 RT DNA polymerase. HIV-1 inhibitor-30 has highly antiretroviral activity against seven non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains (RT-K103N; RT-Y181C; RT K103N,Y181C; RT-L100I,K103N; RT-Y188L; RT-K103N,G190A; RT-K103N,V108I) with IC50s of 0.04~1.42 μM. HIV-1 inhibitor-30 can be used for researching AIDS.
2138861-99-9	ABBV-744 ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers.
214287-99-7	BMS 561390
2162956-63-8	Salvianan A
216699-07-9	Abacavir sulfate Abacavir is an antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC50 value of 5.3 μM.
2170506-18-8	HIV-1-inhibitor-36 HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1. HIV-1 inhibitor-36 has the potential for further development as novel latency reversing agent.
217082-57-0	Apelin-17 (Human, Bovine) Apelin-17 (human, bovine) is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 2.5 nM that is secreted by adipocytes. It potently inhibits forskolin-stimulated cAMP production in vitro.
217178-62-6	Stampidine Stampidine is a possible next-generation Pre-exposure prophylaxis (PrEP) candidate to prevent the sexual transmission of HIV-1.
2189684-45-3	GS-CA-1 GS-CA-1 is a novel HIV capsid inhibitor developed by Gilead, which is a promisingly long-acting antiretroviral (ARV) agent. The preclinical study showed that GS-CA-1 could inhibit HIV-1 replication in human peripheral blood mononuclear cells (PBMCs) (EC50 = 140 pM).
219944-39-5	Isoescin IA Source from the herbs of Aesculus hippocastanum L.
220408-24-2	HIV-1-TAT(48-60) HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.
220751-00-8	Hypoglaunine D Hypoglaunine D, an analogue of triptonine B, is an anti-HIV compound that inhibits HIV replication in H9 lymphocytes with an EC50 of 22 μg/mL.
221662-50-6	L-2'-Fd4C
2219362-41-9	GS-9822 GS-9822 is one of novel non-catalytic site integrase inhibitors (NCINIs), which is a potential class of antiretroviral (ARV) agents. GS-9822 exhibits a potent effect against the T174I mutant (EC50: 3.0 ± 0.9 nM) and IN polymorphic variants (fold shift: 0.4 to 1.3). Studies showed that it has excellent pharmacokinetic properties and metabolic stability.
2234273-72-2	NBD-14189 NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV 1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50<200 nM).
223769-59-3	HIV-Protease-Substrate-1 HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease.
2245231-10-9	Pirmitegravir Pirmitegravir is a potent and first-in-class allosteric integrase (ALLINI) inhibitor that targets LEDGF/p75 binding site, and has excellent antiviral and safety properties. It shows picomolar IC50 in human PBMCs with a therapeutic index of >24000 for HIV-1.

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