-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
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- Flavivirus
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- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
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- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- Virus Protease
- West Nile virus
- Antiviral intermediates
Decanoyl-RVKR-CMK-TFA
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2098497-25-5 |
| Description | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication. |
Product Information
| Synonyms | Decanoyl-RVKR-CMK (TFA)|HY-107760A |
| Molecular Weight | 858.43 |
| Molecular Formula | C36H67ClF3N11O7 |
| Purity | 96.40% |
| Solubility | In Vitro: H2O : 4 mg/mL(4.66 mM;Need ultrasonic) |
| Appearance | White to off-white (Solid) |
| Storage | Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 years * In solvent -80°C 6 months -20°C 1 month (sealed storage, away from moisture and light) |
| In Vitro | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell. Decanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF. Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition). |
| Target | HIV |
Description of First Aid Measures
Eye contact
Remove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.
Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.
InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.
IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.