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Antiviral API
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Decanoyl-RVKR-CMK-TFA
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Category | Human immunodeficiency Virus (HIV) |
CAS | 2098497-25-5 |
Description | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication. |
Product Information
Synonyms | Decanoyl-RVKR-CMK (TFA)|HY-107760A |
Molecular Weight | 858.43 |
Molecular Formula | C36H67ClF3N11O7 |
Purity | 96.40% |
Solubility | In Vitro: H2O : 4 mg/mL(4.66 mM;Need ultrasonic) |
Appearance | White to off-white (Solid) |
Storage | Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 years * In solvent -80°C 6 months -20°C 1 month (sealed storage, away from moisture and light) |
In Vitro | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell. Decanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF. Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition). |
Target | HIV |