Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
2395777-43-0	HIV-1-inhibitor-33 HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 M in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS.
2395777-45-2	HIV-1-inhibitor-34 HIV-1 inhibitor-34 (compound 5q) is a potent and selective HIV-1 inhibitor with an EC50 of 6.4 nM for HIV-1 and a CC50 of 16 M in MT-4 cells. HIV-1 inhibitor-34 can be used for researching AIDS.
2396382-78-6	HIV-1 capsid inhibitor 1
24027-80-3	2',3'-Dideoxyadenosine 5'-Triphosphate ddATP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddATP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dATP in cells.
2408729-03-1	HIV-IN-4 HIV-IN-4 (Compound 12) is a potent inhibitor of HIV. HIV-IN-4 shows promising anti-HIV activities.
2409099-32-5	Semzuvolimab
2411819-82-2	NBD-14270 NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100M).
2414099-82-2	HIV-1-inhibitor-39 HIV-1 inhibitor-39 (compound 3c) is a potent HIV-1 inhibitor with an EC50 of >112.88 µM. HIV-1 inhibitor-39 shows anti-RT (HIV-1 reverse transcriptase) activities with an IC50 of 15.75 µM. HIV-1 inhibitor-39 shows cytotoxicity for MT-4 cells with an CC50 of 112.9 µM.
2415504-88-8	HIV-1-inhibitor-26 HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS.
2416971-32-7	HIV-1-inhibitor-35 HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent.
2416971-40-7	HIV-1 inhibitor-37
2416971-48-5	HIV-1-inhibitor-38 HIV-1 inhibitor-38 (Compound 91) is a potent HIV-1. HIV-1 inhibitor-38 has the potential for further development as novel latency reversing agents.
2417048-11-2	GSK878
2417213-75-1	Zinlirvimab
2442512-14-1	Fipravirimat dihydrochloride
2447-57-6	Sulfadoxine Sulfadoxine is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax. Sulfadoxine is an ultra-long-lasting sulfonamide previously used in combination with pyrimethamine to treat or prevent malaria. Due to high levels of resistance, its use is no longer recommended routinely.
2450-53-5	Isochlorogenic acid A 3,5-Di-O-caffeoylquinic acid isolated from the flowerbud of Lonicera japonica Thunb. It has hepatoprotective and potent anti-hepatitis B activities.
2457357-99-0	FNC-TP FNC-TP is the intracellular active form of FNC which is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.
2459929-46-3	HIV-1-inhibitor-42 HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 .
2459929-62-3	HIV-IN-5 HIV-IN-5 is an investigational small molecule with potent inhibitory activity against HIV-1, demonstrating an IC50 of 0.16 μM. It targets key components of the HIV lifecycle, such as reverse transcriptase, integrase, or protease, and effectively inhibits HIV DNA-dependent DNA polymerization with an IC50 of 2.18 μM. By binding to the NNRTI binding pocket (NNIBP) on the reverse transcriptase enzyme, HIV-IN-5 disrupts viral replication, reduces viral load, and slows disease progression, making it a promising candidate for inclusion in antiretroviral therapies for managing and treating HIV/AIDS.

※ Please kindly note that our services are for research use only.