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Virus Protease

CAS No. Product Name Inquiry
DV-B-120
Encephalitic alphavirus-IN-1
Encephalitic-alphavirus-IN-1
Encephalitic alphavirus-IN-1 has antiviral activity for VEEV and EEEV with EC50s of 0.24 μM and 0.16 μM, respectively.
FGA145
FGA146
Furin-IN-2
GZNL-P36
IAV-IN-3
L-Lysine-15N-1 dihydrochloride
Mpro inhibitor N3 hemihydrate
Mpro inhibitor N3 hemihydrate is a potent SARS-CoV-2 Mpro inhibitor with an EC50 of 16.77 μM for SARS-CoV-2. It specifically inhibits Mpro in a variety of coronaviruses, including SARS-CoV and MERS-CoV. It inhibits HCoV-229E, FIPV and MHV-A59 with individual IC50 of 4.0, 8.8, and 2.7 μM, respectively.
Mpro/Cathepsin L-IN-1
NHC-triphosphate tetraammonium
NHC-triphosphate tetraammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
NS2B-NS3-IN-2
NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 µM.
NS2B-NS3-IN-3
NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease.
NS2B-NS3-IN-4
NS2B/NS3-IN-4 (Compound 34e) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.69 µM and 1.04 µM against DENV2 and ZIKV NS2B/NS3 proteases, respectively.
NS2B-NS3-IN-5
NS2B/NS3-IN-5 (Compound 25b) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 µM and 4.38 µM against ZIKV and DENV2 NS2B/NS3 proteases, respectively.
NS2B-NS3-IN-7
NS2B/NS3-IN-7 (compound 26) is a highly potent Zika virus NS2B-NS3 protease inhibitor with a Ki value of 2.33 nM.
NS2B-NS3pro-IN-1
NS2B-NS3pro-IN-2
NSC89641

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