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Encephalitic-alphavirus-IN-1

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Category Virus Protease
Description Encephalitic alphavirus-IN-1 has antiviral activity for VEEV and EEEV with EC50s of 0.24 μM and 0.16 μM, respectively.
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Product Information

Synonyms Encephalitic alphavirus-IN-1|HY-145842|CS-0434183
Molecular Weight 484.52
Molecular Formula C27H25FN6O2
Canonical SMILES CC1=NC=C(C=C1)C2=C3C(=CC(=C2)C#N)C(=O)N(C4C(=N3)N(CCN4C)C)C5=CC(=C(C=C5)OC)F
Purity ≥98% (HPLC)
Density 1.2±0.1 g/cm3
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 906
Exact Mass 484.20230222
Index Of Refraction 1.637
In Vitro Encephalitic alphavirus-IN-1 (1 and 5 μM; 18 hours) reduces substantial VEEV and EEEV in human brain primary neuronal cells.
Target EC50: 0.24 μM (VEEV), 0.16 μM (EEEV)
XLogP3-AA 2.9

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