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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Virus Protease
CAS No. | Product Name | Inquiry |
---|---|---|
1185047-73-7 |
Mangostin-[d3]Mangostin-[d3] is the labelled analogue of Mangostin, which is an anti-inflammatory agent. |
|
131-04-4 |
Palmatine-hydroxidePalmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities. |
|
1429192-00-6 |
Retro-2Retro-2 is a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface between the endosome and trans-Golgi network. It has been shown to be effective against a range of bacterial and virus pathogens, both in vitro and in animal models. |
|
14737-89-4 |
(E)-3,4-Dimethoxycinnamic acid(E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid, which has anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. |
|
1613465-33-0 |
ML-336ML-336 is a quinazolinone-based inhibitor of Venezuelan Equine Encephalitis Virus (VEEV). It inhibits VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and Trinidad donkey). |
|
1821-12-1 |
4-Phenylbutyric acidA chemical chaperone involved in protein-folding disorders. |
|
2135640-93-4 |
(+)-JNJ-A07(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models. |
|
2222042-47-7 |
As-358As-358 has inhibitory effects against Ebola virus and Marburg virus, with IC50s of 47.5 μM and 3.7 μM. |
|
223537-30-2 |
RupintrivirRupintrivir is a potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). It has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. It blocks processing of viral proteins, thus blocking viral replication. |
|
2316-26-9 |
3,4-Dimethoxycinnamic acid, predominantly trans3,4-Dimethoxycinnamic acid isolated from the leaves of Phyllostachys heterocycla. |
|
23288-49-5 |
ProbucolEnhances selective uptake of HDL-associated cholesteryl esters. |
|
2374723-26-7 |
As-358-hydrochlorideAs-358 (hydrochloride) has inhibitory effects against Ebola virus and Marburg virus with IC50s of 9.1 μM and 18.1 μM, as well as exhibits good in vivo safety. |
|
2459657-57-7 |
NS2B-NS3-IN-6NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. |
|
263707-16-0 |
ESI-09ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation, as well as EPAC-mediated insulin secretion in pancreatic β cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer. |
|
2708934-53-4 |
CCF0058981CCF0058981, a non-covalent SARS-CoV-2 3CLpro (SC2) inhibitor (IC50 = 68 nM), can inhibit SARS-CoV-1 3CLpro (SC1) with an IC50 of 19 nM. It has antiviral efficacy and has the potential to study COVID-19. |
|
2762166-06-1 |
ZIKV-IN-1ZIKV-IN-1 is a potent zika virus inhibitor with an EC50 of 2.8 µM and EC90 of 6.8 µM. ZIKV-IN-1 shows anti-ZIKV activity with low cytotoxicity. ZIKV-IN-1 shows a strong affinity to ZIKV RdRp domain. |
|
30462-35-2 |
Theaflavin 3,3'-digallateTheaflavin 3,3'-digallate is a flavonoid isolated from Black tea. It is a good antitumor agent as well. |
|
329221-38-7 |
AX20017AX20017 is a highly selective PknG inhibitor. It acts by blocking the proliferation of M. tuberculosis. AX20017 is shown to completely inactivate PknG-mediated blockage of lysosomal transfer and degradation of M. bovis BCG in macrophages at concentrations (10μM or higher) that does not otherwise affect the growth of BCG outside its infected host. |
|
3486-67-7 |
PalmatinePalmatine could potentially be developed for the treatment of flavivirus infections.Palmatine is an inhibitor of dopamine generation. |
|
358730-86-6 |
4-Phenylbutyric Acid-[d11]4-Phenylbutyric acid-d11 (4-PBA-d11) is the deuterium labeled 4-Phenylbutyric acid. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research. |
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