Influenza Virus

CAS No.	Product Name	Inquiry
14142-64-4	Cletoquine oxalate Cletoquine oxalate, a chloroquine derivative, is resistant to chikungunya virus (CHIKV) and is produced in the liver by CYP2D6, CYP3A4, CYP3A5 and CYP2C8 isoenzymes. It has antimalarial effects and can be used to study autoimmune diseases.
1428247-78-2	IHVR-17028 IHVR-17028, a potent and broad-spectrum antiviral drug used in infectious disease research, has antiviral activity against BVDV, TCRV and DENV with EC50s of 0.4, 0.26 and 0.3 μM, respectively. It is a potent inhibitor of ER α-glucosidase I with an IC50 of 0.24 μM.
1428729-63-8	RIG-1 modulator 1 RIG-1 modulator 1 is an inhibitor of HBV, HCV and HIV.
1438272-42-4	MBX2329 MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains.
145572-44-7	Sophocarpine Monohydrate Sophocarpine is an effective agent for treating colonic inflammation.
14617-17-5	Triperiden Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism drug.
146954-74-7	2'-Deoxy-5'-O-DMT-2'-fluoro-uridine It is used for RNA synthesis and nucleoside modification.
1469988-63-3	QL-X-138 QL-X-138 is a potent and selective BTK/MNK dual kinase inhibitor, exhibiting covalent binding to BTK and non-covalent binding to MNK. QL-X-138 shows IC50s of 9.4 nM, 107.4 nM and 26 nM for BTK, MNK1 and MNK2 kinases respectively. QL-X-138 can be used for the research of B-cell malignancies.
14919-49-4	3,4'-Dihydroxyflavone 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus.
1501-84-4	Rimantadine hydrochloride Rimantadine hydrochloride, also called as Flumadine, is a nucleic acid synthesis inhibitor and an anti-influenza virus drug.
15473-63-7	Rupestonic-acid Rupestonic acid, a sesquiterpene, can inhibit influenza virus.
160003-66-7	Iniparib BSI-201 is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair. PARP-1 catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks.
1629869-44-8	VX-787 VX-787, a pyrrolopyridine derivative, has been found to be an antiviral agent and is still under Phase II trial against Influenza A virus infection.
1638211-04-7	ML303 ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1.
1644156-41-1	DHODH-IN-9 DHODH-IN-9, an azine-bearing analogue, is a human dihydroorotate dehydrogenase inhibitor with antiviral effect (pMIC50 = 7.4).
1644156-56-8	hDHODH-IN-4 hDHODH-IN-4 is a potent inhibitor of human dihydroorotate dehydrogenase (DHODH), with a pIC50 of 7.8 for human recombinant DHODH. It inhibits measles virus replication, with a pMIC50 of 8.8.
1644156-80-8	hDHODH-IN-3 hDHODH-IN-3, a human dihydroorotate dehydrogenase inhibitor, inhibits measles virus replication with a pMIC50 of 8.6.
171094-50-1	Zanamivir-hydrate(5:1) Zanamivir hydrate (5:1) is the hydrate of Zanamivir. Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively
1777807-64-3	ZINC03129319 ZINC03129319, an activator of stimulator of interferon genes (STING), is a dengue virus (DENV) NS2B-NS3 protease inhibitor with inhibition constants (Ki1) of 92 μM and Ki3 of 20 μM. (Extracted from patent US20150141521A1)
1807887-16-6	Antiviral-agent-19 Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC50 of 1.3 µM.

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