Influenza Virus

CAS No.	Product Name	Inquiry
2411584-06-8	Influenza-virus-IN-2 Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 μM and a CC50 of 150.85 μM. Influenza virus-IN-2 has concentration-dependent inhibitory activity against PAN endonuclease, with an EC50 of 489.39 nM. Influenza virus-IN-2 exhibits activity against influenza A virus.
2412451-16-0	Influenza-virus-IN-3 Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 µM.
2415788-71-3	Cap-dependent-endonuclease-IN-25 Cap-dependent endonuclease-IN-25 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-25 is a macrocyclic pyridotriazine derivative. Cap-dependent endonuclease-IN-25 has the potential for the research of viral infections caused by viruses belonging to the Orthomyxoviridae family.
2416258-53-0	Cap-dependent-endonuclease-IN-5 Cap-dependent endonuclease-IN-5 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-5 inhibits influenza virus well, and/or has lower cytotoxicity, better in vivo pharmacokinetic properties and in vivo pharmacodynamic properties.
24316-19-6	Cephalotaxine Antiviral and antitumor agent.
2454680-16-9	Cap-dependent-endonuclease-IN-8 Cap-dependent endonuclease-IN-8 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-8 inhibits replication of orthomyxoviruses (including influenza A, influenza B and influenza C).
2460686-97-7	Cap-dependent-endonuclease-IN-12 Cap-dependent endonuclease-IN-12 (EXP-35) is a potent Cap-dependent endonuclease inhibitor with low cytotoxicity. Cap-dependent endonuclease-IN-12 shows inhibitory activity against H1N1.
2464415-12-9	Influenza-A-virus-IN-5 Influenza A virus-IN-5 (Compound 16e) is a potent, orally active anti-influenza A virus (IAV) agent with an IC50 of 1.29 μM.
2464415-31-2	Influenza-A-virus-IN-6 Influenza A virus-IN-6 (compound 16j) is a potent and selective influenza A virus inhibitor with an IC50 of 3.88 µM and CC50 of 36.64 µM. Influenza A virus-IN-6 shows anti-IAV activity with low cytotoxicity.
2464415-40-3	Influenza-A-virus-IN-7 Influenza A virus-IN-7 (compound 16r) is a potent and orally active influenza A virus inhibitor with an IC50 of 3.43 µM and 50 of >100 µM. Influenza A virus-IN-7 shows anti-IAV activity with low cytotoxicity. Influenza A virus-IN-7 inhibits the transcription and replication of viral RNA
2473524-63-7	Neuraminidase-IN-5 Neuraminidase-IN-5 (Compound 5b) is a potent inhibitor of neuraminidase with an IC50 of 0.02 μM. Neuraminidase (NA) is a promising target for development of anti-influenza drugs. Neuraminidase-IN-5 is a dihydrofurocoumarin derivative compound.
2478446-18-1	Zanamivir-Cholesterol Conjugate Zanamivir-cholesterol conjugate, a long-acting neuraminidase inhibitor, has potent efficacy against drug-resistant influenza viruses.
2481321-20-2	Anti-Influenza agent 3
2485715-97-5	Cap-dependent-endonuclease-IN-7 Cap-dependent endonuclease-IN-7 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-7 Inhibits the synthesis of viral mRNA and eventually inhibits virus proliferation. Cap-dependent endonuclease-IN-7 has the potential for the research of viral infections (including influenza A, influenza B and influenza C).
2489248-15-7	Cap-dependent-endonuclease-IN-6 Cap-dependent endonuclease-IN-6 (compound 13) is a cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-6 shows inhibition against influenza virus (EC50=38.21 nM).
24967-27-9	N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid is a potent neuraminidase (sialidase) inhibitor. It shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively.
251359-24-7	M2e-human M2e, human, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A, which is a valid and versatile vaccine candidate to protect against any strain of human influenza A.
2540881-21-6	UH15-38
254750-02-2	Emricasan Emricasan is a pan-caspase inhibitor with antiapoptotic and antiinflammatory activity. It was shown that emricasan decreased caspase activity, serum alanine aminotransferase (ALT), and hepatic fibrogenesis in a murine model of non-alcoholic steatohepatitis. Emricasan has been granted fast track designation by the FDA for the treatment of non-alcoholic steatohepatitis cirrhosis.
2567929-06-8	Cap-dependent-endonuclease-IN-19 Cap-dependent endonuclease-IN-19 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-19 is a spirocyclic pyridone derivative. Cap-dependent endonuclease-IN-19 has strong inhibitory effect on RNA polymerase activity of A virus.

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