Influenza Virus

CAS No.	Product Name	Inquiry
157-03-9	6-Diazo-5-oxo-L-nor-Leucine It is produced by the strain of Streptomyces ambofaciens. It has anti-tumor activity and is not suitable for clinical use due to excessive toxicity. Its N-acetyl (Duazomycin) also has anti-tumor effect.
160003-66-7	Iniparib BSI-201 is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair. PARP-1 catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks.
162666-34-4	Flutimide
1627115-50-7	Influenza virus-IN-8
1629869-44-8	VX-787 VX-787, a pyrrolopyridine derivative, has been found to be an antiviral agent and is still under Phase II trial against Influenza A virus infection.
1638211-04-7	ML303 ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1).
1644156-41-1	DHODH-IN-9 DHODH-IN-9, an azine-bearing analogue, is a human dihydroorotate dehydrogenase inhibitor with antiviral effect (pMIC50 = 7.4).
1644156-56-8	hDHODH-IN-4 hDHODH-IN-4 is a potent inhibitor of human dihydroorotate dehydrogenase (DHODH), with a pIC50 of 7.8 for human recombinant DHODH. It inhibits measles virus replication, with a pMIC50 of 8.8.
1644156-80-8	hDHODH-IN-3 hDHODH-IN-3, a human dihydroorotate dehydrogenase inhibitor, inhibits measles virus replication with a pMIC50 of 8.6.
170380-69-5	1,4-Epidioxybisabola-2,10-dien-9-one 1,4-Epidioxybisabola-2,10-dien-9-one is isolated from the leaves of Alpinia intermedia.
171094-50-1	Zanamivir-hydrate(5:1) Zanamivir hydrate (5:1) is the hydrate of Zanamivir. Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively
174605-64-2	L-742001 Hydrochloride
175669-29-1	Polycarpine hydrochloride
1777807-64-3	ZINC03129319 ZINC03129319, an activator of stimulator of interferon genes (STING), is a dengue virus (DENV) NS2B-NS3 protease inhibitor with inhibition constants (Ki1) of 92 μM and Ki3 of 20 μM. (Extracted from patent US20150141521A1)
1795138-23-6	Ketotifen-d3 Fumarate Ketotifen-[d3] fumarate is the labelled salt of Ketotifen, which is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. Ketotifen is used as an antiasthmatic and antiallergic agent.
1807887-16-6	Antiviral-agent-19 Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC50 of 1.3 µM.
1807954-17-1	Gedivumab
1807960-57-1	Lesofavumab
18133-22-7	Netropsin Dihydrochloride It is a basic cytotoxic polypeptide produced by the strain of Streptomyces netropsis. It is a DNA minor groove binding ligand.
181373-35-3	NS1-IN-1 NS1-IN-1 (compound 3) is a potent NS1 inhibitor. NS1 is a major influenza A virus virulence factor that inhibits host gene expression. NS1-IN-1 decreases viral protein levels, contributing to the reduction of virus replication. NS1-IN-1 shows antiviral activity by repressing the activity of mTORC1 in a TSC1-TSC2-dependent manner.

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