Influenza Virus

CAS No.	Product Name	Inquiry
2200336-20-3	Onradivir Onradivir is a significantly better anti-influenza virus agent. (Extracted from patent WO2021047437 A1)
220803-19-0	N-Acetylneuraminic-acid-13C-2 N-Acetylneuraminic acid-13C-2 is the 13C labeled N-Acetylneuraminic acid. N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
2215863-74-2	Urumin
2217630-64-1	Neuraminidase-IN-9 Neuraminidase-IN-9 (Compound 6l) is a potent influenza neuraminidase inhibitor with IC50 values of 0.12, 0.049 and 0.16 µM against H5N1, H5N2 and H5N6, respectively.
2218480-15-8	Neuraminidase-IN-12
2222067-23-2	Neuraminidase-IN-13
2241664-16-2	JNJ4796 JNJ4796 is an oral active influenza virus fusion inhibitor.
2250313-14-3	Influenza A virus-IN-1 Influenza A virus-IN-1, a dihydropyrrolidone derivative, is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50s of 3.11-7.13 μM. It effectively inhibits the replication of IAV and up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA.
2265911-12-2	XSJ2-46
23094-71-5	Chebulagic acid Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease.
2364589-86-4	Cap-dependent-endonuclease-IN-3 Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-3 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-3 has the potential for the research of influenza A and influenza B infection.
2367587-02-6	Viral polymerase-IN-1 hydrochloride
2375241-19-1	Onradivir monohydrate
2378640-67-4	PAN endonuclease-IN-1
2379438-80-7	Compound Y-1 Compound Y-1 is a neuraminidase inhibitor with IC50 of 0.21 μM. Compound Y-1 exhibits activity against H1N1 influenza virus.
2390067-58-8	Influenza-A-virus-IN-4 Influenza A virus-IN-4 (compound 23b), an Oseltamivir derivative, is a potent inhibitor of neuraminidase. Influenza A virus-IN-4 exerts powerful inhibitions on Influenza Viruses.
2395007-75-5	RSV-IAV-IN-2 RSV/IAV-IN-2 (compound 14c) is a potent and dual inhibitor of RSV/IAV. RSV/IAV-IN-2 has lesser cytotoxicity than the clinical drug, Ribavirin. RSV/IAV-IN-2 has the potential for the research of RSV and/or IAV infections.
2395007-77-7	RSV-IAV-IN-1 RSV/IAV-IN-1 (compound 14e) is a potent and dual inhibitor of RSV/IAV. RSV/IAV-IN-1 has lesser cytotoxicity than the clinical drug, Ribavirin. RSV/IAV-IN-1 has the potential for the research of RSV and/or IAV infections.
2395007-81-3	RSV-IAV-IN-3 RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage.
2407570-07-2	Antiviral-agent-20 Antiviral agent 20 is a selective inhibitor against Zika virus infection with an EC50 of 4.5 µM.

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