SARS-CoV

CAS No.	Product Name	Inquiry
	SARS-CoV-2-IN-74
	SARS-CoV-2-IN-77
	SARS-CoV-2-IN-79
	SARS-CoV-2-IN-8 SARS-CoV-2-IN-8 is an inhibitor of SARS-CoV-2 main protease with an IC50 value of 0.75 μM.
	SARS-CoV-2-IN-81
	SARS-CoV-2-IN-83
	SARS-CoV-2-IN-87
	SARS-CoV-2-IN-88
	SARS-CoV-2-IN-90
	SARS-CoV-2-IN-91
	SARS-CoV-2-IN-93
	SARS-CoV-IN-5
	Simeprevir-13C,d3
	Simeprevir-13C-d3 Simeprevir-13C,d3 (TMC435-13C,d3) is the 13C- and deuterium labeled Simeprevir. Simeprevir is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir inhibits HCV replication with an 50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses.
	SP-inhibitor-1 SP inhibitor 1 (compound 34) is a selective SARS-CoV-2 spike protein (SP) inhibitor with an IC50 of 3.26 μM, >25 μM, >25 μM for SP, Mpro and PLpro protein, respectively. SP inhibitor 1 is a vitro SARS-CoV-2 replication inhibitor at non-toxic concentrations (0.3250<5.98 μM). SP inhibitor 1 shows cellular antiviral activity.
	SPR38
	SPR39
	SPR41
	Telaprevir-d4 Telaprevir-d4 (VX-950-d4) is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide. Telaprevir inhibits SARS-CoV-2 3CLpro activity.
	Tipranavir-d7

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