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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
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Telaprevir-d4
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| Category | HCV Protease |
| Description | Telaprevir-d4 (VX-950-d4) is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide. Telaprevir inhibits SARS-CoV-2 3CLpro activity. |
Product Information
| Synonyms | Telaprevir-d4|HY-10235S|CS-0374234 |
| Molecular Weight | 683.87 |
| Molecular Formula | C36H53N7O6 |
| Canonical SMILES | CCCC(C(=O)C(=O)NC1CC1)NC(=O)C2C3CCCC3CN2C(=O)C(C(C)(C)C)NC(=O)C(C4CCCCC4)NC(=O)C5=NC=CN=C5 |
| Purity | ≥98% (HPLC) |
| Density | 1.25±0.1 g/cm3 (20 °C, 760 mmHg) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 1240 |
| Exact Mass | 683.43083942 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| PSA | 179.56000 |
| Target | HCV Protease; HCV; SARS-CoV |
| XLogP3-AA | 4.2 |
