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SP-inhibitor-1

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Category SARS-CoV
Description SP inhibitor 1 (compound 34) is a selective SARS-CoV-2 spike protein (SP) inhibitor with an IC50 of 3.26 μM, >25 μM, >25 μM for SP, Mpro and PLpro protein, respectively. SP inhibitor 1 is a vitro SARS-CoV-2 replication inhibitor at non-toxic concentrations (0.3250<5.98 μM). SP inhibitor 1 shows cellular antiviral activity.
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Product Information

Synonyms SP inhibitor 1|HY-144647|CS-0433382
Molecular Weight 530.7
Molecular Formula C36H38N2O2
Canonical SMILES CC(C)CN1C=C(C2=C1C=CC(=C2)C(=O)OC)CN(CCC3=CC=C(C=C3)C4=CC=CC=C4)CC5=CC=CC=C5
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 750
Exact Mass 530.293328459
PSA 54.13000
Target SARS-CoV; Virus Protease
XLogP3-AA 8

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