Hepatitis B Virus (HBV)

CAS No.	Product Name	Inquiry
163252-36-6	Clevudine Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active.
202138-50-9	Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate.
298708-81-3	BAY 41-4109 BAY 41-4109 is a novel drug inhibiting hepatitis B virus capsid formation and replication.
1011529-10-4	Azvudine Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV.
87085-00-5	Mulberrofuran G Mulberrofuran G isolated from the root bark of Morus alba L.
65995-63-3	Punicalagin Punicalagin is an ellagitannin, a type of phenolic compounds. It had a greater antifungal activity against T. rubrum. It has the potential to be developed as an alternative or supplemental agent for prevention of Salmonella infection. After being absorbed by the human body, punicalagin can be decomposed into ellagic acid under the action of human enzymes. It has excellent antioxidant properties and has been used as a food antioxidant. It is now mostly used in cosmetics.
1181216-83-0	Schisanwilsonin H Schisanwilsonin H is a lignan found in the fruits of Schisandra wilsoniana.
211567-04-3	Picroside IV Picroside IV is a compound of the iridoids found in the roots of Picrorhiza scrophulariiflora.
1351931-30-0	Sanggenol P Sanggenol P is a natural flavonoid found in the root bark of Morus alba L.
93413-00-4	Chamaechromone Chamaechromone is isolated from the roots of Stellera chamaeja sme. Chamaechromone can undergo extensive phase I and phase II metabolism in rat. Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2.
82508-31-4	Pseudolaric acid B Pseudolaric acid B (PAB), which comes from the bark of Pseudolarix kaempferi Gordon, has diverse effects that are relevant to cancer therapy, including apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo. pseudolaric acid B can trigger apoptosis by decreasing Bcl-2 levels and activating caspase-3 protease. The future development of PAB as a cancer therapeutic is ongoing. Besides, PAB significantly suppressed proliferation of DU145 cells in a dose-dependent manner without obvious cytotoxicity. PAB may inhibit growth of HRPC DU145 cells and induce apoptosis through ROS generation and Bcl-2 degradation via the activation of the ubiquitin-proteasome pathway.
142340-99-6	Adefovir Dipivoxil Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).
134678-17-4	Lamivudine Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS.
209216-23-9	Entecavir monohydrate Entecavir triphosphate is a highly potent inhibitor of wild-type HBV Pol and is 100- to 300-fold more potent than lamivudine triphosphate against 3TC-resistant HBV Pol. It competes with dGTP to be incorporated into viral DNA.
25316-40-9	Doxorubicin hydrochloride Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
484-12-8	Osthol Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material.
443683-76-9	Alisol F 24-acetate Alisol F 24-acetate represents a naturally sourced product that may possess a broad range of bioactivities. This product has gained particular interest as a reference standard in Qianghuo studies, a traditional Chinese medicinal herb, acknowledged to exhibit anti-rheumatic, anti-cold, and anti-headache properties. Alisol F 24-acetate reveals promising anti-tumor capacities and demonstrates potential as a therapeutic approach for inflammatory conditions.
155521-45-2	Alisol F Alisol F is a natural product, which is extracted from the tubers of Alisma plantago-aquatica Linn. It suppresses iNOS induction.

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