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Adefovir Dipivoxil

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Category Hepatitis B Virus (HBV)
CAS 142340-99-6
Description Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).
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Synonyms ADEFOVIR DIPIVOXIL;142340-99-6;Hepsera;Preveon;Adefovir pivoxil;bis-POM PMEA;GS-0840;GS 840;GS 0840;Adefovir di(pivaloyloxymethyl) ester;GS-840;Adefovir dipivoxil [USAN];[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate;9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;DTXSID5046487;UNII-U6Q8Z01514;9-(2-((-Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;Adefovir pivoxil (JAN);(((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate;Adefovir dipivoxil (USAN);U6Q8Z01514;Propanoic acid, 2,2-dimethyl-, (((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) ester;DTXCID3026487;CHEBI:31175;adefovir depivoxil;MFCD00869897;((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid, diester with hydroxymethyl pivalate;((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate);NCGC00164624-01;Adefovirdipivoxl;ADEFOVIR PIVOXIL [JAN];9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine;ADEFOVIR DIPIVOXIL (MART.);ADEFOVIR DIPIVOXIL [MART.];YouHeDing;[({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl 2,2-dimethylpropanoate;Bis(pom)PMEA;SMR002530072;Hepsera (TM);Hepsera (TN);Piv2PMEA;CAS-142340-99-6;Bis(POM)-PMEA;Adefovirdipivoxil;adefovir-dipivoxil;(((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxymethanediyl) bis(2,2-dimethylpropanoate);({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphoryl)bis(oxymethanediyl) bis(2,2-dimethylpropanoate);[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid, diester with hydroxymethyl pivalate;Adefovir Dipivoxil?;Adefovir dipivoxil- Bio-X;CHEMBL922;SCHEMBL29729;MLS003915635;MLS004774124;Bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine;ADEFOVIR DIPIVOXIL [VANDF];BCPP000434;HMS3604F09;HMS3655I04;ADEFOVIR DIPIVOXIL [WHO-DD];BCP22959;HY-B0255;Tox21_112243;BDBM50248359;s1718;STL257088;ADEFOVIR DIPIVOXIL [EMA EPAR];Adefovir Dipivoxil (Preveon, Hepsera);AKOS005145737;Tox21_112243_1;AB07592;AC-1693;BCP9000232;CCG-269700;DB00718;GS-3604;ADEFOVIR DIPIVOXIL [ORANGE BOOK];NCGC00164624-02;NCGC00164624-03;NCGC00164624-11;"Adefovir Dipivoxil (Preveon, Hepsera)";BA164139;BCP0726000157;NS00005343;SW219933-1;D01655;SBI-0653850.0001;AB01274706-01;AB01274706_02;A807894;ADEFOVIR DI(PIVALOYLOXYMETHYL) ESTER [MI];Adefovir dipivoxil 100 microg/mL in Acetonitrile;SR-01000931258;Q-101927;SR-01000931258-2;BRD-K96159438-001-03-0;BRD-K96159438-001-06-3;BRD-K96159438-001-07-1;Z1546616202;Adefovir dipivoxil, Antibiotic for Culture Media Use Only;9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine;Bis(Pivaloyloxymethyl)-9-[(R)-2-(Phosphonomethoxy)Ethyl]Adenine;Bis(2,2-dimethylpropanonyloxymethyl) (2-(6-amino-9H-purin-9-yl)ethoxymethyl)phosphate;((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)-bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate);(((2-(6-AMINO-9H-PURIN-9-YL)ETHOXY)METHYL)PHOSPHORYL)BIS(OXY)BIS(METHYLENE) BIS(2,2-DIMETHYLPROPANOATE);2,2-dimethylpropanoic acid [2-(6-aminopurin-9-yl)ethoxymethyl-[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphoryl]oxymethyl ester;Adefovir dipivoxyl;3-{[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}-8,8-dimethyl-3-oxido-7-oxo-2,4,6-trioxa-3lambda~5~-phosphanon-1-yl 2,2-dimethylpropanoate;
IUPAC Name [2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
Molecular Weight 501.47
Molecular Formula C20H32N5O8P
Canonical SMILES NC1=C2N=CN(CCOCP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C2=NC=N1
InChI InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)
InChIKey WOZSCQDILHKSGG-UHFFFAOYSA-N
Melting Point 100-102 °C
Purity >98%
Appearance White Solid
Application Reverse Transcriptase Inhibitors
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

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