SARS-CoV

CAS No.	Product Name	Inquiry
1208232-55-6	Gallinamide-A Gallinamide A is a potent inhibitor of cathepsin L with an IC50 value of 17.6 pM.
1215326-44-5	F594-1001
1216432-56-2	Hydroxychloroquine-[d4] Sulfate Hydroxychloroquine-[d4] Sulfate is an isotope labelled compound of Hydroxychloroquine Sulfate, an antimalarial, antirheumatic and lupus erythematosus suppressant. It is a COVID-19-related research product.
1217653-15-0	Mefloquine-[d9] Hydrochloride Mefloquine-[d9] Hydrochloride is the labelled analogue of Mefloquine Hydrochloride. Mefloquine Hydrochloride is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
1217819-15-2	Tipranavir-[d4] Tipranavir-[d4] is the labelled analogue of Tipranavir, which is a nonpeptidic HIV protease inhibitor and has been found to be effective as an antiviral.
1225177-95-6	Covidcil-19
123307-75-5	RBT-9
123606-06-4	Riamilovir
1236278-28-6	Clazakizumab Clazakizumab is a monoclonal antibody directed against interleukin-6. Clazakizumab has been undergoing a clinical trial for the treatment of CABMR in recipients of a kidney transplant.
1236310-35-2	SARS-CoV-2 Mpro-IN-22
124027-58-3	Kobophenol A Kobophenol A is a natural product found in Caragana korshinskii and Carex folliculata. Kobophenol A blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. It inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 μM.
1241946-89-3	Simeprevir sodium salt Simeprevir is an orally bioavailable inhibitor of the hepatitis C virus (HCV) NS3/4A protease. It has been approved in combination with peginterferon-alfa and ribavirin for the treatment of HCV and HBV infections.
1254-47-3	Fluphenazine hydrochloride
1256751-11-7	Boceprevir-[d9] Boceprevir-[d9] is a stable isotopic labelled compound of Boceprevir. Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection.
1260244-33-4	SARS-CoV-2-IN-20 SARS-CoV-2-IN-20 (Compound 1a) is a potent inhibitor of SARS-CoV-2 with an EC50 of 6.5 μM. SARS-CoV-2-IN-20 has the potential for the research of infection diseases. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals.
1261253-79-5	AT-9010 AT-9010 is a potent inhibitor of NiRAN which is a function essential for viral replication. AT-9010 can inhibit SARS-CoV-2 replication.
1265624-68-7	SARS-CoV-2-IN-57
127373-66-4	Sivelestat Sivelestat is a competitive human neutrophil elastase (HNE) inhibitor (IC50 = 44 nM, Ki = 0.2 μM). It also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse (IC50 = 19 to 49 nM). However, it does not inhibit trypsin, thrombin, plasmin, plasma kallikrein, pancreas kallikrein, chymotrypsin and cathepsin G even at 100 μM. In in-vivo studies, it suppressed lung hemorrhage in hamster (ID50 = 82 μg/kg) by intratracheal administration and increase of skin capillary permeability in guinea pig (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase.
1282451-83-5	PLpro/RBD-IN-1
128345-62-0	Ranitidinebismuthcitrate Ranitidine bismuth citrate is an orally active Histamine H2-receptor antagonist with an IC50 of 3.3 μM. Ranitidine bismuthcitrate has high selectivity for SARS-CoV-2-infected cells. Ranitidine bismuth citrate is a commonly used agent anti-Helicobacter pylori infection with an MIC90 value of 16 ng/L.

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