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Respiratory syncytial Virus (RSV)

CAS No. Product Name Inquiry
FNC-TP trisodium
FNC-TP trisodium is the intracellular active form of FNC which is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.
GS-7682
HIV-1 inhibitor-58
JNJ-8003
Mitoxantrone-d8 dihydrochloride (N-carboxymethyl)valine Daclatasvir TFA
RSV-IN-10
RSV-IN-11
VV116
VV116 (JT001) is an orally active nucleoside antiviral agent against SARS-CoV-2 and respiratory syncytial virus (RSV) infection. VV116 has favorable oral bioavailability, excellent in vitro antiviral activity and selectivity.
1064-06-8
Quercetin pentaacetate
Quercetin pentaacetate interacts with RSV and inhibits the viral adhesion on cell surface.
1071517-39-9
Setrobuvir (ANA598)
Setrobuvir (ANA598) is an orally active non-nucleosidic HCV NS5B polymerase inhibitor. ANA-598 inhibits both de novo RNA synthesis and primer extension, with IC50s between 4 and 5 nM. Setrobuvir also shows excellent binding affinity to SARS- CoV-2 RdRp and induces RdRp inhibition.
114637-83-1
3,4-Di-O-caffeoyl quinic acid methyl ester
1903763-82-5
Sisunatovir
Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection.
156722-18-8
Rostafuroxin
Rostafuroxin is a Na+/K+ ATPase modulator that treats hypertension by normalizing renal Na+/K+ ATPase pump function.
1353625-73-6
Presatovir
Presatovir is a viral fusion protein inhibitor with EC50 value of 0.43 nM. It can inhibit a broad range of respiratory syncytial virus clinical isolates by blocking the virus-cell fusion process. It can also inhibit pre- to post-fusion conformational changes of the respiratory syncytial virus fusion protein. Phase II clinical trials for the treatment of respiratory syncytial virus infections is ongoing.
1617-53-4
Amentoflavone
Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone.
1092103-22-4
ent-11β-Hydroxyatis-16-ene-3,14-dione
ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity.
162401-32-3
Roflumilast
Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy.

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