Respiratory syncytial Virus (RSV)

CAS No.	Product Name	Inquiry
	VV116 VV116 (JT001) is an orally active nucleoside antiviral agent against SARS-CoV-2 and respiratory syncytial virus (RSV) infection. VV116 has favorable oral bioavailability, excellent in vitro antiviral activity and selectivity.
1064-06-8	Quercetin pentaacetate Quercetin pentaacetate interacts with RSV and inhibits the viral adhesion on cell surface.
1071517-39-9	Setrobuvir (ANA598) Setrobuvir (ANA598) is an orally active non-nucleosidic HCV NS5B polymerase inhibitor. ANA-598 inhibits both de novo RNA synthesis and primer extension, with IC50s between 4 and 5 nM. Setrobuvir also shows excellent binding affinity to SARS- CoV-2 RdRp and induces RdRp inhibition.
1189992-00-4	Roflumilast-[d3] A deuterated Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).
1323077-88-8	(S)-Enzaplatovir (S)-Enzaplatovir is the S-enantiomer of Enzaplatovir. It shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV).
1323077-89-9	Enzaplatovir Enzaplatovir (BTA-C585) is an orally bioavailable fusion inhibitor for respiratory syncytial virus (RSV) infection.
1355050-21-3	GS-443902 trisodium GS-443902 trisodium is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively.
1355149-45-9	GS-443902 GS-443902 is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively.
1398065-69-4	Roflumilast-[d4] One of the isotopic labelled form of Roflumilast, which is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).
1422500-60-4	Ziresovir Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species.
1445379-92-9	ALS-8176 (active form) ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay.
1445385-02-3	Lumicitabine Lumicitabine is an inhibitor of the respiratory syncytial virus (RSV) polymerase. It is a prodrug that converts to plasma-circulating ALS-8112, and then to the 5'-active nucleoside triphosphate (NTP) form within host cells.
1794760-31-8	Roflumilast N-oxide-[d4] A deuterated impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).
1902114-15-1	PC786 PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. It exhibits potent antiviral activity against RSV-A and RSV-B.
1903763-83-6	Sisunatovir hydrochloride Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection.
1903763-82-5	Sisunatovir Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection.
156722-18-8	Rostafuroxin Rostafuroxin is a Na+/K+ ATPase modulator that treats hypertension by normalizing renal Na+/K+ ATPase pump function.
1353625-73-6	Presatovir Presatovir is a viral fusion protein inhibitor with EC50 value of 0.43 nM. It can inhibit a broad range of respiratory syncytial virus clinical isolates by blocking the virus-cell fusion process. It can also inhibit pre- to post-fusion conformational changes of the respiratory syncytial virus fusion protein. Phase II clinical trials for the treatment of respiratory syncytial virus infections is ongoing.
1617-53-4	Amentoflavone Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone.
1092103-22-4	ent-11β-Hydroxyatis-16-ene-3,14-dione ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity.

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