SARS-CoV

CAS No.	Product Name	Inquiry
2758359-91-8	SARS-CoV-2-Mpro-IN-1 SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible inhibitor of SARS-CoV-2 main protease(Mpro), with an IC50 of 116 nM.
2761911-40-2	SARS-CoV-2-IN-16 SARS-CoV-2-IN-16 (Compound 12) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-16 exhibits potent anti-viral activity with the EC50 of 3.69 μM. SARS-CoV-2-IN-16 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-16 is a potent NPro ligand.
2761911-44-6	SARS-CoV-2-IN-17 SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC50 of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand.
2765088-93-3	SARS-CoV-2-3CLpro-IN-2 SARS-CoV-2 3CLpro-IN-2 (Compound 1) is a potent inhibitor of 3CL protease. SARS-CoV-2 3CLpro-IN-2 has the potential for the research of SARS-CoV-2 diseases.
2768834-39-3	SARS-CoV-MPro-IN-2 SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in drug discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19.
278603-08-0	NH125 NH125 is a potent and selective eEF-2 kinase inhibitor with an IC50 of 60 nM, and also a potent histidine kinase inhibitor. It shows >125-fold selectivity over PKC, PKA, and CaMKII.
30021-77-3	Cleistanthin B Cleistanthin B has a role as an antihypertensive agent. It is a member of cleistanthins, Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells.
31377-23-8	1-Adamantanamine sulfate Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. It also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research.
34580-13-7	Ketotifen Ketotifen is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators, used as self-medication for the temporary relief of itching of the eye due to allergic conjunctivitis (ophthalmic).
34973-27-8	NHC-triphosphate N 4-Hydroxycytidine (NHC) is an antiviral ribonucleoside analog that acts as a competitive alternative substrate for virally encoded RNA-dependent RNA polymerases. NHC-triphosphate is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
3545-67-3	Chloroquine Dihydrochloride Chloroquine diphosphateis an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
358731-91-6	Dexamethasone-[d5] Dexamethasone-[d5] is the labelled analogue of Dexamethasone, which is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation and inhibits the induction of nitric oxide synthase.
36791-04-5	Ribavirin Ribavirin is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor.
37693-01-9	Clofoctol Clofoctol is a bacteriostatic antibiotic used to against gram-positive bacteria.
39023-73-9	NHC-diphosphate N 4-Hydroxycytidine (NHC) is an antiviral ribonucleoside analog that acts as a competitive alternative substrate for virally encoded RNA-dependent RNA polymerases. NHC-diphosphate is an active phosphorylated form.
50906-56-4	Arteannuin B Arteannuin B is a natural sesquiterpenoid found in the herbs of Artemisia annua, it exhibits potent antimalarial activity and has potential antitumor activity.
50924-49-7	Mizoribine Bredinin is a nucleoside antibiotic produced by Eupenicillum brefeldianum M-2166. It has anti-L-5178Y cell and anti-pox virus activity, not against bacteria and fungi,
51773-92-3	Mefloquine Hydrochloride Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
522660-61-3	SARS-CoV-2-nsp13-IN-2 SARS-CoV-2 nsp13-IN-2 (Compound C2) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 42 μM against nsp13 ssDNA+ ATPase.
529-53-3	Scutellarein Scutellarin and Scutellarein could improve neuronal injury, and Scutellarein had better protective effect than scutellarin in rat cerebral ischemia.

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