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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
SARS-CoV
CAS No. | Product Name | Inquiry |
---|---|---|
531-58-8 |
CichoriinAesculetin-7-O-D-Glucopyranoside is isolated from chicory. |
|
54-05-7 |
ChloroquineAn antimalarial agent. |
|
56961-10-5 |
SARS-CoV-2-IN-13SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals. |
|
57685-46-8 |
Kansuinine BKansuinine B from Euphorbia kansui L, inhibits IL-6-induced Stat3 activation. It could be used in the study for COVID-19. |
|
582-24-1 |
2-Hydroxyacetophenone2-Hydroxyacetophenone (CAS# 582-24-1) is a useful reactant for synthesis of diarylpyrazoles as cyclooxygenase 2 inhibitors. |
|
58581-89-8 |
AzelastineAzelastine, a phthalazine derivative, is a potent, second-generation, selective, histamine antagonist used as a first line therapy of mild intermittent. |
|
611-75-6 |
Bromhexine hydrochlorideBromhexine is a mucolytic (expectorant) agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties. |
|
61422-45-5 |
CarmofurCarmofur or HCFU is a pyrimidine analogue used as an antineoplastic agent. It is a derivative of fluorouracil. |
|
614-60-8 |
trans-2-Hydroxycinnamic acid2-Hydroxycinnamic acid is found in the herbs of Angraecum fragrans, it has photooxidant activity. |
|
64706-54-3 |
bepridilBepridil ((±)-Bepridil) is a calcium channel blocking agent used as antiarrhythmic agent. Bepridil inhibits both calcium and sodium currents, has research potential in certain ischemia-induced ventricular arrhythmias. Bepridil also has strong inhibition of SARS-CoV-2 from entry and replication inside Vero E6 and A549 cells. |
|
65666-07-1 |
SilymarinSilymarin is a flavonolignan, obtained from milk thistle (Silybum marianum) plant. It exhibits in vitro antiviral, antibacterial, antifungal activities and cytotoxicity. |
|
665026-57-3 |
BananinBananin is an effective adamantane-related molecule with antiviral activity, which has the potential for SARS-CoV research. |
|
67526-95-8 |
ThapsigarginPotent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations. In cells, sarco/endoplasmic calcium ATPases (SERCAs) transport free calcium into the sarcoplasmic and endoplasmic reticula, lowering intracellular calcium levels to stop signaling through this cation. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. In vivo, thapsigargin and related sesquiterpene lactones have anti-inflammatory and anti-cancer effects. |
|
69235-50-3 |
Acriflavine-hydrochlorideAcriflavine hydrochloride is a potent HIF-1 inhibitor, with antitumor activity. It also has antimicrobial and antiviral activities. Acriflavine hydrochloride is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2. |
|
714923-33-8 |
FWM-3FWM-3 is a potent SARS-CoV-2 NSP13 helicase inhibitor. |
|
76684-89-4 |
E 64cE-64c is a cysteine protease inhibitor used for detecting autophagy in plants. |
|
778270-11-4 |
GNF-2GNF-2 is a Bcr-Abl inhibitor that binds to the myristoyl binding pocket, an allosteric site distant from the active site, stabilizing the inactive form of the kinase. Thus, it can selectively inhibit Bcr-Abl phosphorylation (IC50 = 267 nM) without affecting native c-Abl or a panel of 63 additional kinases. |
|
80251-32-7 |
Nafamostat hydrochlorideNafamostat hydrochloride is a synthetic serine protease inhibitor. It is used as an anticoagulant. It is similar to Tranilast. |
|
81525-10-2 |
NafamostatNafamostat is a broad spectrum serine protease inhibitor and kallikrein inhibitor. It inhibits blood coagulation and used as an anticoagulant. It is also a possible complement inhibitor. It is mainly used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. It is formulated with HCl salt due to its basic tendencies. |
|
850876-88-9 |
DanoprevirDanoprevir(ITMN-191;R7227; RO5190591;RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. |
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