SARS-CoV

CAS No.	Product Name	Inquiry
2140-72-9	2'-O-Methylcytidine Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
214221-82-6	SARS-CoV-2-IN-84
2144491-78-9	(Rac)-X77 (Rac)-X77 also known as MUN91789, is a potent inhibitor of SARS-CoV-2 main protease.
2172676-02-5	Velpatasvir-[d7] Velpatasvir-[d7] is the labelled analogue of Velpatasvir, which is a selective Hepatitis C virus NS 5 protein inhibitor.
217813-15-5	KW-8232 KW-8232 is an orally active anti-osteoporotic agent. It can reduce the biosynthesis of PGE2.
22203-98-1	SARS-CoV-2-IN-14
222631-44-9	BCX 4430 hydrochloride BCX4430, a novel synthetic adenosine analogue, inhibits infection of distinct filoviruses in human cells. Interfering with the replication process is a well-established antiviral strategy that has been successfully exploited in developing such life-saving drugs as the nucleoside inhibitors of HIV and acyclovir for herpes simplex complex. BCX4430 may be suitable for administration by intravenous (IV), intramuscular (IM), and oral (PO) routes.
223611-93-6	Jobosic acid
2244991-17-9	SARS-CoV-2-IN-19 SARS-CoV-2-IN-19 (Compound 6g) is a potent inhibitor of SARS-CoV-2 with an EC50 of 8.8 μM. SARS-CoV-2-IN-19 shows potent activity against SARS-CoV-2 helicase (nsp13), a highly conserved enzyme, highlighting a potentiality against emerging HCoVs outbreaks. SARS-CoV-2-IN-19 has the potential for the research of infection diseases.
2245195-67-7	HeE1-2Tyr HeE1-2Tyr and related derivatives were originally discovered as inhibitors of the RdRp of flaviviruses, which significantly inhibit SARS-CoV-2 RdRp.
2245697-92-9	MERS-CoV-IN-1 MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus, which has the potential for COVID-19 research.
2258606-34-5	RMC-113
229975-97-7	Atazanavir Sulfate Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. It is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus.
2305607-27-4	Dexamethasone-d4 Dexamethasone-d4 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
2305638-98-4	Enibarcimab Enibarcimab is a humanized monoclonal antibody that has been investigated as a medication for the treatment of acute heart failure and COVID-19.
2309384-85-6	NIP-22c
23094-71-5	Chebulagic acid Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease.
233277-99-1	K777 K-11777 is a potent, irreversible cysteine protease inhibitor. Besides, K11777 is not only a substrate but also a mechanism-based inhibitor of CYP3A4.
2350285-18-4	SARS-CoV-2-IN-62
2350285-21-9	SARS-CoV-2-IN-63

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