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Orthopoxvirus

CAS No. Product Name Inquiry
Indometacin-d7
Thiamine-monochloride-C13-hydrochloride
Thiamine monochloride-C13 hydrochloride is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central Metabolic enzymes.
100986-85-4
Levofloxacin
Levofloxacin is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Levofloxacin achieves higher concentrations in the serum and tissue of mice than does ciprofloxacin.
1134181-96-6
Thymidine-d14
1191-85-1
Eicosatetraynoic acid
ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells.
120964-45-6
3-deazaneplanocin A (DZNeP) HCl
3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.
1268015-38-8
NIOCH-14
NIOCH 14 is a antiviral agent and a pro-drug. NIOCH 14 has antiviral activity against orthopoxviruses. NIOCH 14 can significantly lower proportions of infected mice, and virus production levels in the lungs. NIOCH 14 can be used for researching anti-smallpox. NIOCH 14 shows anti-orthopoxvirus activity.
127757-45-3
Cyclic-HPMPC
Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model.
132376-92-2
Thymidine-[5',5''-d2]
Thymidine-[5',5''-d2] is the labelled analogue of Thymidine, which is a constituent of deoxyribonucleic acid.
138199-71-0
Levofloxacin hydrate
The hydrate form of Levofloxacin, an Ofloxacin derivative, could be commonly used as an antibacterial agent through influencing DNA replication. It is an antibiotic with activity against gram-negative bacteria.
1476-53-5
Novobiocin sodium
Novobiocin Sodium is a very potent bacterial DNA gyrase and human organic anion transporter with Kis of 14.87±0.40 μM for hOAT1, 4.77±1.12 μM for hOAT3 and 90.50±7.50 μM for hOAT4.
152819-48-2
HOE961
HOE961, the diacetate ester prodrug of S2242, is active against respiratory cowpox virus infections, is orally active in infection models.
156968-81-9
Thymidine-13C5
As the labelled form of Thymidine, Thymidine-[1',2',3',4',5'-13C5] is a constituent of deoxyribonucleic acid.
177325-13-2
Levofloxacin hydrochloride
Levofloxacin Hydrochloride is potent fluoroquinolone antibiotic utilized in the treatment of a wide range of bacterial infections, including pneumonia, chronic bronchitis, sinusitis, and skin infections. By targeting bacterial DNA gyrase, it effectively hinders DNA replication and transcription processes, thereby exerting its antimicrobial effects.
18133-22-7
Netropsin Dihydrochloride
It is a basic cytotoxic polypeptide produced by the strain of Streptomyces netropsis. It is a DNA minor groove binding ligand.
185553-96-2
Thymidine-[2'-13C]
As the labelled version of Thymidine, Thymidine-[2'-13C] is a constituent of deoxyribonucleic acid.
240407-53-8
Thymidine-[5'-13C]
As the labelled form of Thymidine, Thymidine-[5'-13C] is a constituent of deoxyribonucleic acid.
25526-93-6
3'-Deoxy-3'-fluorothymidine(ALOVUDINE)
It is an antiviral agent, DNA polymerase inhibitor and HIV inhibitor.
267243-28-7
Canertinib
Canertinib is an experimental drug candidate for the treatment of cancer. It is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 = 0.8 nM), HER-2 (IC50 = 19 nM) and ErbB-4 (IC50 = 7 nM).
303-81-1
Novobiocin
Novobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the interaction of both p23 and Hsp70 co-chaperones with the Hsp90 complex. (IC50=700μmol/L)

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