Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
107900-76-5	Ganodermanondiol Ganodermanondiol is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Study shows that Ganodermanondiol exhibits the inhibitory effect on the proliferation of HL60 and K562 human tumor cells.
55319-36-3	Soyasaponin II Soyasaponin II is found in Glycine max, it shows antiviral effects.
1180-71-8	Limonin Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.
379270-37-8	Tenofovir Alafenamide Tenofovir Alafenamide is a prodrug of Tenofovir, which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.
1611493-60-7	Bictegravir Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection.

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