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Human immunodeficiency Virus (HIV)

CAS No. Product Name Inquiry
Reverse transcriptase-IN-4
Ritonavir-13C,d3
Ritonavir-13C-d3
Ritonavir-13C,d3 (ABT 538-13C,d3) is the 13C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
Ritonavir-d6
Ritonavir-d6 (ABT 538-d6) is the deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
Ritonavir-d8
Seletracetam-lithium
Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.
Tat-beclin 1 TFA
TC14012 TFA
TH6342
Tipranavir-d7
Valproic acid-d14 sodium
Valproic-acid-d14-sodium
Valproic acid-d14-sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 M), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, Metabolic disease, HIV infection and prevention of migraine headaches.
Valproic-acid-d4-sodium
Valproic acid-d4-sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 M), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, Metabolic disease, HIV infection and prevention of migraine headaches.
Zidovudine-13C,d3
Zidovudine-13C-d3
Zidovudine-13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.
Zidovudine-d3
Zidovudine-d3 (Azidothymidine-d3) is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase
inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.
Zidovudine-d4
ZLM-66
ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTIs) with an IC50 of 41 nM for wild-type (WT) HIV-1 reverse transcriptase and an EC50 value of 13 nM for wild-type HIV-1. ZLM-66 is a Doravirine (HY-16767) analogs. ZLM-66 can be used for the research of AIDS.
9011-18-1
Dextran sulfate sodium salt
Dextran sulfate sodium salt is a long chain polymer of sulfated glucose, containing 17 - 20% sulfur. It has been used as an anticoagulant and has been shown to inhibit the binding of HIV-1 to CD4+ T lymphocytes. It is used to accelerate hybridization of DNA probes to immobilized nucleic acids.
865363-93-5
2'-Deoxy-4'-ethynyl-2-fluoroadenosine
Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.

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