Human immunodeficiency Virus (HIV)

all Activators (8) Antagonists (4) Inducer (1) Inhibitors (721)

CAS No.	Product Name	Inquiry
	Tipranavir-d7
	Valproic acid-d14 sodium
	Valproic-acid-d14-sodium Valproic acid-d14-sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 M), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, Metabolic disease, HIV infection and prevention of migraine headaches.
	Valproic-acid-d4-sodium Valproic acid-d4-sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 M), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, Metabolic disease, HIV infection and prevention of migraine headaches.
	Zidovudine-13C,d3
	Zidovudine-13C-d3 Zidovudine-13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.
	Zidovudine-d3 Zidovudine-d3 (Azidothymidine-d3) is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.
	Zidovudine-d4
	ZLM-66 ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTIs) with an IC50 of 41 nM for wild-type (WT) HIV-1 reverse transcriptase and an EC50 value of 13 nM for wild-type HIV-1. ZLM-66 is a Doravirine (HY-16767) analogs. ZLM-66 can be used for the research of AIDS.
9011-18-1	Dextran sulfate sodium salt Dextran sulfate sodium salt is a long chain polymer of sulfated glucose, containing 17 - 20% sulfur. It has been used as an anticoagulant and has been shown to inhibit the binding of HIV-1 to CD4+ T lymphocytes. It is used to accelerate hybridization of DNA probes to immobilized nucleic acids.
865363-93-5	2'-Deoxy-4'-ethynyl-2-fluoroadenosine Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
7585-39-9	β-Cyclodextrin β-cyclodextrin is a cyclic oligosaccharide produced from starch via enzymatic conversion. It is widely used in food, medicine, cosmetics, chemical and other industries. β-cyclodextrin is used as a complexing agent in drug delivery, increasing the water solubility, dissolution rate and bioavailability of poorly water-soluble drugs. β-Cyclodextrin is commonly used to produce HPLC columns that allow the separation of chiral enantiomers.
1246817-56-0	Tizoxanide-[d4] Tizoxanide-[d4] is the labelled analogue of Tizoxanide. Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses.
1262770-70-6	Sulfadoxine-[d3] Sulfadoxine-[d3] is the labelled analogue of Sulfadoxine, which is an antibacterial. It competitively inhibits dihydropteroate synthase and interferes with folic acid synthesis.
1330266-05-1	Sulfadoxine-[d4] Sulfadoxine-[d4] is the labelled analogue of Sulfadoxine. Sulfadoxine is an antibacterial. It competitively inhibits dihydropteroate synthase, interfering with folate synthesis.
1142095-93-9	Etravirine-[d4] Etravirine-[d4] is the labelled analogue of Etravirine, which is a drug used for the treatment of HIV and a non-nucleoside reverse transcriptase inhibitor (NNRTI).
880549-30-4	Mavorixafor hydrochloride AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay.
110078-46-1	Plerixafor Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
606968-52-9	FC131 FC 131 is a CXCR4 antagonist with anti-HIV activity.
497223-25-3	Cenicriviroc Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection.

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