Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
	HIV-1-protease-IN-6 HIV-1 protease-IN-6 (compound 17d) is a potent HIV-1 protease inhibitor, with an IC50 of 21 pM and a Ki of 4.7 pM, respectively. HIV-1 protease-IN-6 exhibits potent antiviral activity to DRV (darunavir)-resistant variant, even more than wild. type virus
	HIV-1-protease-IN-7 HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM).
	HIV-IN-3 HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV with an IC50 of 1.5 μM. HIV-IN-3 has the potential for the research of HIV- related diseases.
	HIV-Protease-Substrate-1-TFA HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease.
	Imperatorin-d6
	Lamivudine-15N,d2
	Megestrol acetate-d3-1
	Megestrol-acetate-d3-1 Megestrol acetate-d3-1 is deuterium labeled Megestrol acetate. Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia.
	Miltefosine-d9 Miltefosine-d9 (HePC-d9) is the deuterium labeled Miltefosine. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT).
	Nelfinavir-d4
	NNRT-IN-4
	ONX-0914 TFA ONX-0914 TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. It blocks cytokine production and attenuates the progression of experimental arthritis, and reactivates latent HIV-1 through HSF-1-mediated p-TEFb activation. It is a non-competitive and irreversible mycobacterial proteasome inhibitor with a Ki of 5.2 μM.
	ONX-0914-TFA ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 TFA blocks cytokine production and attenuates progression of experimental arthritis.
	Panobinostat-d4 hydrochloride
	Panobinostat-d4-hydrochloride Panobinostat-d4 (hydrochloride) is deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells. Panobinostatinduces cell Apoptosis and Autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma.
	Peldesine-dihydrochloride Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively
	PROTAC Vif degrader-1
	PTP1B-IN-25
	Raltegravir-13C,d3 potassium
	Reverse transcriptase-IN-3

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