Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
	HIV-1 inhibitor-41
	HIV-1 inhibitor-44
	HIV-1 inhibitor-58
	HIV-1 inhibitor-59
	HIV-1 inhibitor-62
	HIV-1 inhibitor-63
	HIV-1 inhibitor-68
	HIV-1 protease-IN-3
	HIV-1 protease-IN-4
	HIV-1-inhibitor-11 HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.
	HIV-1-inhibitor-12 HIV-1 inhibitor-12 is potent HIV-1 inhibitor. HIV-1 inhibitor-12 inhibits HIV-1 capsid protein polymerization with an IC50 of 9 nM.
	HIV-1-inhibitor-13 HIV-1 inhibitor-13 (compound 16c) is a orally active and potent HIV-1 non nucleoside reverse transcriptase inhibitor (NNRTI), with IC50 of 0.14 μM (HIV-1 RT). HIV-1 inhibitor-13 shows activity against a panel of HIV-1 resistant strains, with EC50 values of 2.85-18.0 nM.
	HIV-1-inhibitor-14 HIV-1 inhibitor-14 (compound 14b) is a highly potent and broad-spectrum HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor with an EC50 of 0.14 μM for HIV-1 RT. HIV-1 inhibitor-14 has inhibitory activity against HIV-1 WT and resistant strains with EC50s of 5.79 ~ 28.3 nM.
	HIV-1-inhibitor-17 HIV-1 inhibitor-18 (compound V-25i) is a potent HIV-1 capsid inhibitor with an EC50 value of 2.57 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >8.55).
	HIV-1-inhibitor-18 HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51).
	HIV-1-inhibitor-40 HIV-1 inhibitor-40 (Compound 4ab) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an EC50 of 1.9 nM. HIV-1 inhibitor-40 displays weak CYP sensitivity with IC50 values of 5.16 μM and 4.51 μM against CYP2C9 and CYP2C19, respectively. HIV-1 inhibitor-40 has no apparent in vivo acute toxicity.
	HIV-1-inhibitor-41 HIV-1 inhibitor-41 (Compound B23) is an orally active non-nucleoside HIV-1 reverse transcriptase inhibitor with EC50 values of 20.8 nM and 50 nM against HIV-1 WT and mutant E138K strain, respectively. HIV-1 inhibitor-41 shows low hERG, no apparent CYP enzymatic inhibition and no acute toxicity.
	HIV-1-inhibitor-44 HIV-1 inhibitor-44 (compound 11l) is a HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-44 shows inhibitory activity against wild-type HIV-1 strain with an EC50 value of 0.209 μM.
	HIV-1-inhibitor-8 HIV-1 inhibitor-8 is an orally active, low-toxicity and potent HIV(cid:0)1 non-nucleoside reverse transcriptase inhibitor (NNRTI).
	HIV-1-protease-IN-4 HIV-1 protease-IN-4 (Compound II-22) is a potent HIV-1 protease inhibitor. HIV-1 protease-IN-4 is a prodrug of atazanavir.

※ Please kindly note that our services are for research use only.