Human immunodeficiency Virus (HIV)

CAS No.	Product Name	Inquiry
73465-43-7	1-Deoxymannojirimycin HCl It is an inhibitor of α-D-mannosidases (jack bean and calf liver) and mammalian α-L-fucosidase, but it has no glucosidase inhibitory properties.
73536-69-3	Bifendate Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage.
7481-89-2	Zalcitabine Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
77286-66-9	(R)-Edelfosine (R)-Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. It induces apoptosis in human promyelocytic HL-60 leukemic cells and promonocytic U937 leukemic cells.
80930-74-1	Zingibroside R1 Zingibroside R1 is a triterpenoid showing anti-tumor, anti-angiogenic and anti-HIV-1 activity.
81-27-6	Sennoside A Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. Sennoside A can be used in health products. It is an HIV-1 inhibitor that is effective against HIV-1 replication.
82-08-6	Rottlerin Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively).
83314-01-6	Bryostatin 1 Bryostatin 1, a structurally unique macrolactone marine natural product, is a protein kinase C (PKC) activator that binds with high affinity (Ki = 1.35 nM). Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke.
83-85-2	Fuscin Produced by the strain of Oidiodendron fuscum Ag 122 and Camb 111, Fuscin has resistance to gram-positive bacteria and mycobacterium (weak) activity. Fuscin is also an anti-HIV compound and antagonist of CKR-5 (CCR5).
848354-66-5	PTACH PTACH is a SAHA-based novel inhibitor of histone deacetylase (HDAC). It exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1.1 to 9.1 μM. It shows strong activity in cancer cell growth inhibition assay. It inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 μM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer. It could inhibit the cell growth of a variety of lymphoid malignant cells through apoptosis induction, more effectively than SAHA. It upregulated anti-oxidant molecules including peroxiredoxin 1 and 2 and glutathione S-transferase at the protein level. It exhibits cytotoxicity by sustaining ROS at the higher level greater than SAHA.
849234-64-6	4-acetamido-N-(2-amino-5-thiophen-2-ylphenyl)benzamide 4-acetamido-N-(2-amino-5-thiophen-2-ylphenyl)benzamide is a selective HDAC1/2 inhibitor, exhibiting selectivity over class II HDACs 3-8. It shows high-affinity to HDAC1 and HDAC2 with Ki of 0.2 and 1.5 nM, respectively.
857050-63-6	Patentiflorin-A Patentiflorin A is a potent, broadspectrum HIV-1 inhibitor. Patentiflorin A also inhibits HIV drug-resistant strains.
864677-55-4	IT1t IT1t is a selective CXCR4 antagonist with IC50 value of 1.1 nM in calcium mobilization assays.It may be potential useful as anti-HIV agent.
864953-39-9	BMS-663068 Tris BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
86583-19-9	3-Deazaadenosine hydrochloride It is an S-adenosine homocysteine hydrolase inhibitor. It has anti-inflammatory effects, inhibiting leukocyte adhesion and chemotaxis, lymphocyt-mediated cytolysis, phagocytosis, degranulation and NF-κB signal transduction.
868046-19-9	Elsulfavirine Elsulfavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment and prevention of human immunodeficiency virus (HIV) infection.
87-17-2	Salicylanilide Salicylanilide has a wide range of biological activities, including antiviral, anti-inflammatory, antibacterial and so on. It inhibits HIV virus by targeting HIV-1 integrase or reverse transcriptase. It inhibits mycobacterial isocitrate lyase (ICL) and has a significant antimycobacterial effect. It can be used as an antiseptic.
87190-79-2	AzddMeC Az-Dcme is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection.
87745-17-3	Valproic acid-[d4] One of the isotopic labelled form of Valproic Acid, which could be used as an antiepileptic agent.
87745-18-4	Valproic acid-[d6] One of the isotopic labelled form of Valproic Acid, which could be used as an antiepileptic agent.

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