HIV Protease

CAS No.	Product Name	Inquiry
26305-03-3	Pepstatin A Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Isovaleryl-Val-Val-Sta-Ala-Sta (Iva-Val-Val-Sta-Ala-Sta).
149845-06-7	Saquinavir Mesylate Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.
186538-00-1	JE-2147 JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro.
28575-34-0	Pepstatin acetate Acetylpepstatin is an aspartyl protease inhibitor that is effective against HIV-1 and HIV-2 protease.
635728-49-3	Darunavir Ethanolate Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.
206361-99-1	Darunavir Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively.
192725-17-0	Lopinavir An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS.
155213-67-5	Ritonavir Ritonavir is an HIV protease inhibitor. It is often used in a low dose with another protease inhibitor lopinavir. Ritonavir was approved for COVID-19 treatment in combination with Nirmatrelvir.
852936-69-7	20(21)-Dehydrolucidenic acid A 20(21)-Dehydrolucidenic acid A is a triterpenoid compound found in the fruit body of Ganoderma lucidum.
123748-68-5	Escin Ia Escin Ia is a triterpenoid saponin isolated from A. chinensis. It was shown to inhibit HIV-1 protease with IC50 value of 35 μM.
107900-76-5	Ganodermanondiol Ganodermanondiol is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Study shows that Ganodermanondiol exhibits the inhibitory effect on the proliferation of HL60 and K562 human tumor cells.

※ Please kindly note that our services are for research use only.