HIV Protease

CAS No.	Product Name	Inquiry
	ddCTP trisodium
	Dolutegravir-d3 Dolutegravir-d3 (S/GSK1349572-d3) is the deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50 =3.6-5.8 nM).
	Nelfinavir-d4
	NNRT-IN-3
	Pepstatin Ammonium
	Pepstatin Trifluoroacetate
	Pepstatin-Ammonium Pepstatin Ammonium is a specific aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease.
	Pepstatin-Trifluoroacetate Pepstatin Trifluoroacetate (Pepstatin A Trifluoroacetate) is a specific aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin- proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease
	Ritonavir-13C-d3 Ritonavir-13C,d3 (ABT 538-13C,d3) is the 13C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
	Ritonavir-d6 Ritonavir-d6 (ABT 538-d6) is the deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
	Ritonavir-d8
1030595-07-3	CL-197
103424-74-4	Herpes virus inhibitor 2
1133378-37-6	Darunavir-[d9] Darunavir-[d9] is a labelled Darunavir. Darunavir is an antiretroviral medication for the prevention of HIV/AIDS.
1133702-41-6	Fosamprenavir-d4 Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Anti-HIV infection.
1191255-15-8	Ganomycin I Ganomycin I is isolated from the herbs of Ganoderma pfeifferi. Ganomycin I inhibits the activity of HIV-1 protease.
1192224-24-0	Dealkyl Atazanavir An impurity of Atazanavir
1206781-64-7	Ganoderic acid GS-1
1217629-70-3	Nelfinavir-[d3] Nelfinavir-[d3] is the labelled analogue of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor.
1217661-20-5	Amprenavir-[d4] Amprenavir-[d4] is a labelled analogue of Amprenavir. Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP.

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